Results 1 to 10 of about 1,999,235 (294)

Integrative analysis of Poly(A)-seq and RNA-seq reveals transcriptional regulation of poly(A) tail length in tuberculosis. [PDF]

open access: yesMicrobiol Spectr
Tuberculosis (TB) is a serious global health problem, and the molecular mechanisms underlying TB pathogenesis remain poorly understood to date. Differential expression of many genes is an important contributor to TB, and poly(A) tails have previously ...
Tuohetaerbaike B   +10 more
europepmc   +2 more sources

Prediction of Poly(A) Sites by Poly(A) Read Mapping [PDF]

open access: yesPLOS ONE, 2017
RNA-seq reads containing part of the poly(A) tail of transcripts (denoted as poly(A) reads) provide the most direct evidence for the position of poly(A) sites in the genome. However, due to reduced coverage of poly(A) tails by reads, poly(A) reads are not routinely identified during RNA-seq mapping.
Bonfert, Thomas, Friedel, Caroline C.
openaire   +5 more sources

Stress-Induced Leakage Current in p+ Poly MOS Capacitors with Poly-Si and Poly-Si0.7Ge0.3 Gate Material [PDF]

open access: yes, 1999
The gate bias polarity dependence of stress-induced leakage current (SILC) of PMOS capacitors with a p+ polycrystalline silicon (poly-Si) and polycrystalline Silicon-Germanium (poly-Si0.7 Ge0.3) gate on 5.6-nm thick gate oxides has been investigated.
Holleman, J.   +5 more
core   +12 more sources

Poly(Ethylene Glycol)-Poly(Lactic Acid) TLR7 Agonist as a Novel HBsAg Immune Response Stimulant

open access: yesFamily Medicine & Primary Care Review, 2023
Hepatitis B is caused by a hepatitis B virus infection, causing inflammation of the liver. The therapeutic approach used to help treat HBV infection has been based on re-establishing a functioning T cell response and limiting additional negative ...
BRYAN GERVAIS DE LIYIS   +5 more
doaj   +1 more source

Co-Administration of Injected and Oral Vaccine Candidates Elicits Improved Immune Responses over Either Route Alone

open access: yesVaccines, 2020
Infectious diseases continue to be a significant cause of morbidity and mortality, and although efficacious vaccines are available for many diseases, some parenteral vaccines elicit little or no mucosal antibodies which can be a significant problem since
Celine A. Hayden   +7 more
doaj   +1 more source

Electrospinning and Post-Spun Chain Conformations of Synthetic, Hydrophobic Poly(α-amino acid)s. [PDF]

open access: yes, 2020
Electrospinning and post-spun conformations of hydrophobic poly(α-amino acid)s are described in this study. The poly(α-amino acid)s, poly(Gly), poly(L-Ala), poly(L-Val), and poly(L-Leu) were synthesized via corresponding N-carboxy-a-amino acid anhydrides.
Devarayan, Kesavan   +4 more
core   +1 more source

Polyadenylated tail length variation pattern in ultra-rapid vitrified bovine oocytes [PDF]

open access: yesVeterinary World, 2016
Aim: The current study aims at investigating the polyadenylated (poly[A]) tail length of morphologically high and low competent oocytes at different developmental stages.
D. J. Dutta, Himangshu Raj, Hiramoni Dev
doaj   +1 more source

Acoustical investigation of poly(dA).poly(dT), poly[d(A-T)].poly[d(A-T)], poly(A) . poly(U) and DNA hydration in dilute aqueous solutions [PDF]

open access: yesNucleic Acids Research, 1989
Apparent molar adiabatic compressibilities and apparent molar volumes of poly[d(A-T)].poly[d(A-T)], poly(dA).poly(dT), DNA and poly(A).poly(U) in aqueous solutions were determined at 1 degree C. The change of concentration increment of the ultrasonic velocity upon replacing counter ion Cs+ by the Mg2+ ion was also determined for these polymers.
V A, Buckin   +3 more
openaire   +2 more sources

Bioenergy as a Driver for the Development of Green Economy in Russia / Биоэнергетика как драйвер развития зеленой экономики в России

open access: yesBeneficium, 2020
Limited, non-renewable and negative ecological impact of conventional energy sources turned our thinking toward the renewable energy resources (sunlight, water flows, wind, tides, geothermal heat, biofuels) in order to maintain economic development and ...
Natalya A. Vukovic / Наталья А. Вукович   +1 more
doaj   +1 more source

Single molecule poly(A) tail-seq shows LARP4 opposes deadenylation throughout mRNA lifespan with most impact on short tails

open access: yeseLife, 2020
La-related protein 4 (LARP4) directly binds both poly(A) and poly(A)-binding protein (PABP). LARP4 was shown to promote poly(A) tail (PAT) lengthening and stabilization of individual mRNAs presumably by protection from deadenylation (Mattijssen et al ...
Sandy Mattijssen   +4 more
doaj   +1 more source

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