Results 11 to 20 of about 740,120 (268)
A kingdom-wide full-length RNA atlas reveals the evolutionary landscapes of plant poly(A) tails [PDF]
Genome BiologyBackground Poly(A) tails play crucial roles in regulating mRNA degradation and translation, yet their evolutionary dynamics remain largely unexplored. Results Here, we generate a comprehensive full-length RNA atlas of poly(A) tail based on 130 million ...
Yang Chen +17 more
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Poly(Ethylene Glycol)-Poly(Lactic Acid) TLR7 Agonist as a Novel HBsAg Immune Response Stimulant
Family Medicine & Primary Care Review, 2023 Hepatitis B is caused by a hepatitis B virus infection, causing inflammation of the liver. The therapeutic approach used to help treat HBV infection has been based on re-establishing a functioning T cell response and limiting additional negative ...
BRYAN GERVAIS DE LIYIS +5 more
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Vaccines, 2020 Infectious diseases continue to be a significant cause of morbidity and mortality, and although efficacious vaccines are available for many diseases, some parenteral vaccines elicit little or no mucosal antibodies which can be a significant problem since
Celine A. Hayden +7 more
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Polyadenylated tail length variation pattern in ultra-rapid vitrified bovine oocytes [PDF]
Veterinary World, 2016 Aim: The current study aims at investigating the polyadenylated (poly[A]) tail length of morphologically high and low competent oocytes at different developmental stages.
D. J. Dutta, Himangshu Raj, Hiramoni Dev
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Charge Transport in Poly(dG)–Poly(dC) and Poly(dA)–Poly(dT) DNA Polymers [PDF]
Journal of Biological Physics, 2004 We investigate the charge transport in synthetic DNA polymers built up from single types of base pairs. In the context of a polaron-like model, for which an electronic tight-binding system and bond vibrations of the double helix are coupled, we present estimates for the electron-vibration coupling strengths utilizing a quantum-chemical procedure ...
Hennig, Dirk +3 more
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Beneficium, 2020 Limited, non-renewable and negative ecological impact of conventional energy sources turned our thinking toward the renewable energy resources (sunlight, water flows, wind, tides, geothermal heat, biofuels) in order to maintain economic development and ...
Natalya A. Vukovic / Наталья А. Вукович +1 more
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eLife, 2020 La-related protein 4 (LARP4) directly binds both poly(A) and poly(A)-binding protein (PABP). LARP4 was shown to promote poly(A) tail (PAT) lengthening and stabilization of individual mRNAs presumably by protection from deadenylation (Mattijssen et al ...
Sandy Mattijssen +4 more
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High frequency, spontaneous motA mutations in Campylobacter jejuni strain 81-176. [PDF]
PLoS ONE, 2014 Campylobacter jejuni is an important cause of bacterial diarrhea worldwide. The pathogenesis of C. jejuni is poorly understood and complicated by phase variation of multiple surface structures including lipooligosaccharide, capsule, and flagellum. When C.
Krystle L Mohawk +4 more
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Ribosomes slide on lysine-encoding homopolymeric A stretches
eLife, 2015 Protein output from synonymous codons is thought to be equivalent if appropriate tRNAs are sufficiently abundant. Here we show that mRNAs encoding iterated lysine codons, AAA or AAG, differentially impact protein synthesis: insertion of iterated AAA ...
Kristin S Koutmou +5 more
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Genome Biology, 2019 Background Polyadenylation plays a key role in producing mature mRNAs in eukaryotes. It is widely believed that the poly(A)-binding proteins (PABs) uniformly bind to poly(A)-tailed mRNAs, regulating their stability and translational efficiency.
Taolan Zhao +11 more
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