Results 21 to 30 of about 740,120 (268)

A systematic review and meta-analysis of Penner serotype prevalence of Campylobacter jejuni in low- and middle-income countries.

open access: yesPLoS ONE, 2021
IntroductionWhile Campylobacter jejuni is a leading foodborne bacterial pathogen worldwide, it poses a particular risk to susceptible populations in low- and middle-income countries (LMICs).
Tegan N Clarke   +5 more
doaj   +1 more source

The use of aluminum trialkoxide for synthesis of poly (ε-caprolactone) and poly (δ-valerolactone): A comparative study [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2018
Four aluminum(III) trialkoxides, namely Al(III) ethoxide (1), Al(III) isopropoxide (2), Al(III) tert-butoxide (3), and Al(III) sec.-butoxide (4), were employed as initiators for the bulk ring-opening polymerizations of δ-valerolactone (VL) and ...
Jitrayut Jitonnom   +3 more
doaj   +1 more source

Preparation and Properties of an Analogue of Poly(A) and Poly(G): Poly(isoguanylic acid) [PDF]

open access: yesEuropean Journal of Biochemistry, 1976
Isoguanosine-5'-pyrosphosphate, in the presence of an oligonucleotide primer, was polymerized by Escherichia coli polynucleotide phosphorylase under conditions analogous to those required for polymerization of 5'-GMP. The resulting poly(isoguanylic acid), poly(isoG), was a multistranded helix with a stability considerably higher than that of poly(G ...
T, Golas   +3 more
openaire   +2 more sources

The Dynamic Poly(A) Tail Acts as a Signal Hub in mRNA Metabolism

open access: yesCells, 2023
In eukaryotes, mRNA metabolism requires a sophisticated signaling system. Recent studies have suggested that polyadenylate tail may play a vital role in such a system.
Guiying Zhang   +4 more
doaj   +1 more source

Poly A- transcripts expressed in HeLa cells. [PDF]

open access: yesPLoS ONE, 2008
Transcripts expressed in eukaryotes are classified as poly A+ transcripts or poly A- transcripts based on the presence or absence of the 3' poly A tail.
Qingfa Wu   +9 more
doaj   +1 more source

iCLIP analysis of RNA substrates of the archaeal exosome

open access: yesBMC Genomics, 2020
Background The archaeal exosome is an exoribonucleolytic multiprotein complex, which degrades single-stranded RNA in 3′ to 5′ direction phosphorolytically. In a reverse reaction, it can add A-rich tails to the 3′-end of RNA.
Jochen Bathke   +9 more
doaj   +1 more source

Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation

open access: yesFEBS Open Bio, 2023
During their synthesis in the cell nucleus, most eukaryotic mRNAs undergo a two‐step 3′‐end processing reaction in which the pre‐mRNA is cleaved and released from the transcribing RNA polymerase II and a polyadenosine (poly(A)) tail is added to the newly
Juan B. Rodríguez‐Molina   +1 more
doaj   +1 more source

RNA-binding proteins distinguish between similar sequence motifs to promote targeted deadenylation by Ccr4-Not

open access: yeseLife, 2019
The Ccr4-Not complex removes mRNA poly(A) tails to regulate eukaryotic mRNA stability and translation. RNA-binding proteins contribute to specificity by interacting with both Ccr4-Not and target mRNAs, but this is not fully understood.
Michael W Webster   +2 more
doaj   +1 more source

Prediction of Poly(A) Sites by Poly(A) Read Mapping. [PDF]

open access: yesPLoS ONE, 2017
RNA-seq reads containing part of the poly(A) tail of transcripts (denoted as poly(A) reads) provide the most direct evidence for the position of poly(A) sites in the genome.
Thomas Bonfert, Caroline C Friedel
doaj   +1 more source

Evaluation of a poly(lactic-acid) scaffold filled with poly(lactide-co-glycolide)/hydroxyapatite nanofibres for reconstruction of a segmental bone defect in a canine model

open access: yesVeterinární Medicína, 2019
Critical-sized bone defects are a difficult problem in both human and veterinary medicine. To address this issue, synthetic graft materials have been garnering attention.
Jang Won Yun   +3 more
doaj   +1 more source

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