Ribosome-inactivating proteins (RIP) are a family of plant enzymes for which a unique activity was determined: rRMA N-glycosidase at a specific universally conserved position, A4324 in the case of rat ribosomes.
Valbonesi P. +5 more
core +1 more source
The mRNA Poly(A)-Binding Protein: Localization, Abundance, and RNA-Binding Specificity
The poly(A)-binding protein (PABP) binds to the messenger (mRNA) 3'-poly(A) tail found on most eukaryotic mRNAs and together with the poly(A) tail has been implicated in governing the stability and the translation of mRNA. In order to further understand the role of the PABP in these processes, we have undertaken a detailed analysis of the cellular ...
M, Görlach, C G, Burd, G, Dreyfuss
openaire +2 more sources
Mammalian N1-adenosine PARylation is a reversible DNA modification
Poly-ADP-ribosylation (PARylation) is a well-known posttranslational modification of proteins. Here the authors show that beyond proteins also mammalian single-stranded DNA is PARylated in vitro and in vivo.
Michael U. Musheev +6 more
doaj +1 more source
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho +8 more
wiley +1 more source
Estudo de adesão e proliferação celular sobre superfícies de filmes poliméricos modificados por processo de plasma frio com descarga de barreira dielétrica [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.Este trabalho descreve a síntese de filmes poliméricos, sua modificação e a avaliação quanto à adesão de espécies ...
Borges, Adriana de Melo Gallindo
core
Poly(ADP-ribosyl)ation of proteins and germ cell development in hyperthyroid rat testes
The effect of increased serum levels of thyroid hormone (triiodothyronine, T3) on young rat testis spermatogenesis was studied by analysing molecular and morphological parameters.
FARINA, BENEDETTA +7 more
core +1 more source
Sustained release injectables formed "in-situ" for veterinary use [PDF]
Repetitive oral administration of tablets to companion animals is particularly challenging and there is a continuing need for alternative options such as long acting injections or implants.
Sautter, Caroline Anne Françoise
core +1 more source
Paip1 Interacts with Poly(A) Binding Protein through Two Independent Binding Motifs [PDF]
The 3' poly(A) tail of eukaryotic mRNAs plays an important role in the regulation of translation. The poly(A) binding protein (PABP) interacts with eukaryotic initiation factor 4G (eIF4G), a component of the eIF4F complex, which binds to the 5' cap structure.
Roy, Guylaine +5 more
openaire +4 more sources
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
Eukaryotic initiation factor 4B and the poly(A)-binding protein bind eIF4G competitively [PDF]
The eukaryotic translation initiation factor (eIF) 4G functions as a scaffold protein that assembles components of the translation initiation complex required to recruit the 40S ribosomal subunit to an mRNA. Although many eukaryotes express two highly similar eIF4G isoforms, those in plants are highly divergent in size and sequence from one another and
Cheng, Shijun, Gallie, Daniel R.
openaire +2 more sources

