Results 71 to 80 of about 203,778 (305)
AggregatePolymer‐coated nanoparticles are widely studied in the context of nanomedicine and it is therefore of utmost importance to understand not only how their structure but also how their colloidal dynamics are affected by physiologically relevant conditions ...
Ferdinand Otto +6 more
doaj +1 more source
Intrinsic Disorder in Proteins with Pathogenic Repeat Expansions
Molecules, 2017 Intrinsically disordered proteins and proteins with intrinsically disordered regions have been shown to be highly prevalent in disease. Furthermore, disease-causing expansions of the regions containing tandem amino acid repeats often push repetitive ...
April L. Darling, Vladimir N. Uversky
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández +10 more
wiley +1 more source
Bioengineering & Translational MedicineHydrogels are extensively employed in healthcare due to their adaptable structures, high water content, and biocompatibility, with FDA‐approved applications ranging from spinal cord regeneration to local therapeutic delivery.
Eric S. Nealy +13 more
doaj +1 more source
Characterization of mRNA polyadenylation in the apicomplexa. [PDF]
PLoS ONE, 2018 Messenger RNA polyadenylation is a universal aspect of gene expression in eukaryotes. In well-established model organisms, this process is mediated by a conserved complex of 15-20 subunits.
Ashley T Stevens +2 more
doaj +1 more source
Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A) [PDF]
, 1977 A template-dependent RNA polymerase has been isolated from poliovirus-infected cells by assaying for the ability of the enzyme to copy poly(A) complexed to an oligo(U) primer.
Baltimore, David, Flanegan, James B.
core
, 2005 Proteins, chain molecules of amino acids, behave in ways which are similar to each other yet quite distinct from standard compact polymers. We demonstrate that the Flory theorem, derived for polymer melts, holds for compact protein native state ...
Amos Maritan +4 more
core +1 more source
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
The mRNA Poly(A)-Binding Protein: Localization, Abundance, and RNA-Binding Specificity
Experimental Cell Research, 1994 The poly(A)-binding protein (PABP) binds to the messenger (mRNA) 3'-poly(A) tail found on most eukaryotic mRNAs and together with the poly(A) tail has been implicated in governing the stability and the translation of mRNA. In order to further understand the role of the PABP in these processes, we have undertaken a detailed analysis of the cellular ...
M, Görlach, C G, Burd, G, Dreyfuss
openaire +2 more sources
Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination
Cell Reports, 2020 Multiple factors influence translation termination efficiency, including nonsense codon identity and immediate context. To determine whether the relative position of a nonsense codon within an open reading frame (ORF) influences termination efficiency, we quantitate the production of prematurely terminated and/or readthrough polypeptides from 26 ...
Wu, Chan +4 more
openaire +4 more sources