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Poly(ADP‐ribose) polymerase: Molecular biological aspects

BioEssays, 1991
AbstractA number of roles have been ascribed to poly(ADP‐ribose) polymerase* including involvement in DNA repair, cell proliferation, differentiation and transformation. Cloning of the gene has allowed the development of molecular biological approaches to elucidate the structure and the function(s) of this highly conserved enzyme.
Murcia, G   +2 more
openaire   +2 more sources

Poly(ADP-ribose) polymerase: Structure-function relationship

Biochimie, 1995
Dissection of the human poly(ADP-ribose) polymerase (PARP) molecule in terms of its structure-function relationship has proved to be an essential step towards understanding the biological role of poly(ADP-ribosylation) as a cellular response to DNA damage in eukaryotes.
M. Masson   +14 more
openaire   +2 more sources

An Update on Poly(ADP-ribose) Polymerase I-A Brief Review

Mini-Reviews in Medicinal Chemistry, 2023
Kaviarasan Lakshmanan   +2 more
exaly  

Erasable Blot of Poly(ADP-ribose) Polymerase

Analytical Biochemistry, 1994
S, Desnoyers   +3 more
openaire   +2 more sources

Regulation of Poly(ADP-Ribose) Polymerase 1 Activity by Y-Box-Binding Protein 1

Biomolecules, 2020
Olga Lavrik   +2 more
exaly  

Poly(ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic

Ca-A Cancer Journal for Clinicians, 2011
Johann S de Bono   +2 more
exaly  

Reduction of Cognitive and Motor Deficits after Traumatic Brain Injury in Mice Deficient in Poly(ADP-Ribose) Polymerase

Journal of Cerebral Blood Flow and Metabolism, 1999
Robert Clark, Steven Graham
exaly  

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