Results 31 to 40 of about 2,253,495 (194)

alpha-Trifluoromethyl Substituted alpha-Amino Acids and alpha-Hydroxy Acids with Organometallic Moieties in the Side Chain

, 1993
Gaa K, Burger K, Sewald N. alpha-Trifluoromethyl Substituted alpha-Amino Acids and alpha-Hydroxy Acids with Organometallic Moieties in the Side Chain. Heteroatom Chem.
Klaus Burger, Gaa, K., Norbert Sewald, Karl Gaa, Burger, K., Sewald, Norbert ; https://orcid.org/   +5 more
core   +1 more source

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Alkaline decomposition of beta-hydroxy-alpha-amino acids

, 1956
RESP ...
Bremner, J. M.
core   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

A New Strategy for the Synthesis of alpha-Difluoromethyl Substituted alpha-Hydroxy and alpha-Amino Acids

, 1996
Osipov SN, Golubev A, Sewald N, et al. A New Strategy for the Synthesis of alpha-Difluoromethyl Substituted alpha-Hydroxy and alpha-Amino Acids. Journal of Organic Chemistry.
Kolomiets, A.F., Michel, T., Fokin, A.V., Golubev, A., Sewald, Norbert ; https://orcid.org/, Burger, K., Osipov, S.N.   +6 more
core   +1 more source

A Hybrid Magnetic Actuation System for Single‐Input Multistates Stabilization: Application to pH‐Responsive Drug Delivery

Advanced Intelligent Systems, EarlyView.
This study presents an integrated proof‐of‐concept robotic platform for targeted delivery applications. A hybrid magnetic actuation system achieves single‐input (z) multistate stabilization (x, y, ϕ, and θ) for precise capsule transport with submillimeter positioning accuracy.
Sejun Park, Hanbi Park, Suho Lee, Bohyeon Kim, Jiseong Ryu, ChangKyu Yoon, Donghoon Son   +6 more
wiley   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

SYNTHESIS OF 9-HYDROXY-14-AZAPROSTANOIC ACIDS AS POTENTIAL ANTIFERTILITY AND ANTIAGGREGATORY AGENTS.

, 1985
SYNTHESIS OF 9-HYDROXY-14-AZAPROSTANOIC ACIDS AS POTENTIAL ANTIFERTILITY AND ANTIAGGREGATORY ...
BONGSUP. CHO (7963775)
core   +6 more sources

Facile determination of the absolute configurations of alpha-hydroxy acids by chiral derivatization coupled with liquid chromatography-mass spectrometry analysis

, 2013
alpha-Hydroxy acids are commonly encountered in natural bioactive molecules. For convenient determination of the absolute configurations of alpha-hydroxy acids, a simple method, named the "O-Marfey method" was developed using a chiral ...
Lim, Chaemin, Kim, Sanghee, Moon, Kyuho, Oh, Dong-Chan   +3 more
core   +1 more source

An antiaging skin care system containing alpha hydroxy acids and vitamins improves the biomechanical parameters of facial skin

, 2014
Diana Tran, Joshua P Townley, Tanya M Barnes, Kerryn A Greive Ego Pharmaceuticals, Braeside, Victoria, Australia Background: The demand for antiaging products has dramatically increased in recent years, driven by an aging population seeking to maintain ...
Tran D, Barnes TM, Townley JP, Greive KA
core