Results 41 to 50 of about 508,276 (294)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Viscoelastic Properties of Polyacrylamide Nanocomposite Hydrogels Prepared in Electrolyte Media: Effect of Gelant Volume [PDF]

Journal of Petroleum Science and Technology, 2016
In this work, nanocomposite (NC) hydrogels based on polyacrylamide/chromium triacetate were prepared at different reaction mixture (gelant) volumes and their crosslinking process and viscoelastic behaviors were studied.
Jamal Aalaie
doaj   +1 more source

Effect of a friction-reducing additive on the drip irrigation uniformity with sugarcane vinasse

Agronomía Colombiana, 2021
Fertigation using vinasse, a high nutrient residue, is a viable form of complementary soil nutrition. However, it represents a dangerous risk of contamination if not properly disposed of.
Lucas Grogenski Meloca, André Luiz Justi   +1 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Polyacrylamide Ferrogels with Ni Nanowires [PDF]

Materials, 2019
Nickel magnetic nanowires (NWs) have attracted significant attention due to their unique properties, which are useful for basic studies and technological applications, for example in biomedicine. Their structure and magnetic properties were systematically studied in the recent years.
Alexander P. Safronov, Bethanie J. H. Stadler, Joseph Um, Mohammad Reza Zamani Kouhpanji, Javier Alonso Masa, Andrey G. Galyas, Galina V. Kurlyandskaya   +6 more
openaire   +5 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Nano-Fe3O4 attached to Crosslinked sulfonated polyacrylamide (Cross-PAA-SO3H) as high performance catalyst for the synthesis of thiazoles under ultrasonic irradiations [PDF]

Nanochemistry Research, 2019
Nano-Fe3O4 attached to Crosslinked sulfonated polyacrylamide (Cross-PAA-SO3H) as a superior catalyst has been utilized for the preparation of 3-alkyl-4-phenyl-1,3-thiazole-2(3H)-thione derivatives through a three-component reactions of phenacyl bromide ...
Hossein Shahbazi-Alavi, Javad Safaei-Ghomi   +1 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Urea Delays High-Temperature Crosslinking of Polyacrylamide for In Situ Preparation of an Organic/Inorganic Composite Gel

Gels
To address the rapid crosslinking reaction and short stability duration of polyacrylamide gel under high salinity and temperature conditions, this paper proposes utilizing urea to delay the nucleophilic substitution crosslinking reaction among ...
Li Liang, Junlong Li, Dongxiang Li, Jie Xu, Bin Zheng, Jikuan Zhao   +5 more
doaj   +1 more source

Synthesis of polyacrylamide in aqueous solution: solubility

Orbital: The Electronic Journal of Chemistry, 2012
The synthesis of aqueous polyacrylamide solution was evaluated for its solubility in water. The reactions were performed using the acrylamide monomer, solvent and initiator (K2S2O8), with the system under magnetic stirring and heating (60°C) for 4 hours.
Daniela T. Valente, Alcino P. de Aguiar
doaj   +1 more source