Results 71 to 80 of about 749,436 (339)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Preparation and Characterization of Hybrid Nanocomposite of Polyacrylamide/Silica-Nanoparticles [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2013
Polyacrylamides are water soluble macromolecules. These polymers are widely used for flocculation, separation and treatment of solid-liquid phase materials.
Ahmad Rabiee   +3 more
doaj   +1 more source

A Gel Probe Equilibrium Sampler for Measuring Arsenic Porewater Profiles and Sorption Gradients in Sediments: I. Laboratory Development [PDF]

open access: yes, 2008
A gel probe equilibrium sampler has been developed to study arsenic (As) geochemistry and sorption behavior in sediment porewater. The gels consist of a hydrated polyacrylamide polymer, which has a 92% water content.
Campbell, Kate M.   +3 more
core   +3 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Síntese de hidrogéis e cinética de liberação de amônio e potássio Hydrogel synthesis and kinetics of ammonium and potassium release

open access: yesRevista Brasileira de Ciência do Solo, 2008
Hidrogéis produzidos a partir de poliacrilamida (PAAm) foram sintetizados e suas eficiências para liberação controlada de NH4+ e K+ contidos em fertilizantes foram avaliadas.
Fauze Ahmad Aouada   +4 more
doaj   +1 more source

A Study of Flow Properties of Kuwaiti Crude Oil Obtained from Different Sources [PDF]

open access: yesJournal of Petroleum Science and Technology, 2017
The rheological properties of four different Kuwaiti crude oils in the presence of polyacrylamide (PAA) were investigated. PAA was varied at three different concentrations of 25, 50, and 75 ppm to study the viscoelastic properties in the untreated ...
Bader Albusairi, Adam Al-Mulla
doaj   +1 more source

Studies on the non-specific esterases of Saccharomyces cerevisiae : a thesis in partial fulfillment [sic.] of the requirements for the degree of Master of Science in Microbiology at Massey University [PDF]

open access: yes, 1984
Twenty wine-making and three laboratory strains of Saccharomyces cerevisiae were examined for non-specific esterases by Polyacrylamide Gel Electrophoresis.
Dick, Bruce
core  

The Exosome Subunit Rrp44 Plays a Direct Role in RNA Substrate Recognition [PDF]

open access: yes, 2007
The exosome plays key roles in RNA maturation and surveillance, but it is unclear how target RNAs are identified. We report the functional characterization of the yeast exosome component Rrp44, a member of the RNase II family.
Anderson, James T.   +2 more
core   +2 more sources

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

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