Peroxiredoxin III : a candidate for drug resistance to chemotherapy : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Biochemistry at Massey University, Palmerston North, New Zealand [PDF]
, 2008 The development of drug resistance to chemotherapeutic drugs is a serious obstacle in the successful treatment of cancer. New cancer drugs are continually being developed with the goal of increasing the effectiveness of chemotherapy.
Aalderink, Miranda
core
Advanced Science, EarlyView.RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source
Proteomics analysis of human breast milk by two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) coupled with mass spectrometry to assess breast cancer risk. [PDF]
Electrophoresis, 2023 Aslebagh R +6 more
europepmc +1 more source
Electrophoretic study of muscle and eye-lens proteins of three species of nemipterids [PDF]
, 1989 Muscle and eye-lens proteins of three fishes belonging to family Nemipteridae N.japonicus, N.mesoprion and N.delagoae were determined by polyacrylamide gel electrophoresis. Densitometer scanning revealed species specific patlcrn for eye-lens proteins.
Chakraborty, S K
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Advanced Science, EarlyView.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Detection of Glycosaminoglycans by Polyacrylamide Gel Electrophoresis and Silver Staining. [PDF]
J Vis Exp, 2021 LaRiviere WB +5 more
europepmc +1 more source
Expression of a human cartilage procollagen gene (COL2A1) in mouse 3T3 cells. [PDF]
, 1991 Expression in a recombinant system has been difficult to obtain for any of the major fibrillar collagens that require processing by eight or more post-translational enzymes.
Ala-Kokko, Leena +5 more
core +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Two-Dimensional Polyacrylamide Gel Electrophoresis Coupled with Nanoliquid Chromatography-Tandem Mass Spectrometry-Based Identification of Differentially Expressed Proteins and Tumorigenic Pathways in the MCF7 Breast Cancer Cell Line Transfected for Jumping Translocation Breakpoint Protein Overexpression. [PDF]
Int J Mol Sci, 2023 Jayathirtha M +5 more
europepmc +1 more source
Polyacrylamide Gel Electrophoresis
Drug Delivery System, 2023 Yoshimasa Kawaguchi, Yu Mikame
openaire +1 more source