Results 101 to 110 of about 523,208 (360)

LmaPA2G4, a Homolog of Human Ebp1, Is an Essential Gene and Inhibits Cell Proliferation in L. major [PDF]

open access: yes, 2014
We have identified LmaPA2G4, a homolog of the human proliferation-associated 2G4 protein (also termed Ebp1), in aphosphoproteomic screening. Multiple sequence alignment and cluster analysis revealed that LmaPA2G4 is a non-peptidasemember of the M24 ...
Joyce, Michelle V.   +4 more
core   +4 more sources

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

open access: yesAdvanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan   +13 more
wiley   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

open access: yesAdvanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee   +8 more
wiley   +1 more source

Separation of Thylakoid Protein Complexes with Two-dimensional Native-PAGE

open access: yesBio-Protocol, 2018
The hierarchical composition and interactions of the labile thylakoid protein complexes can be assessed by sequential 2D-native gel-electrophoresis system.
Marjaana Rantala   +2 more
doaj   +1 more source

Variation of morphology, karyotype and protein band pattern of adenium (Adenium obesum) varieties [PDF]

open access: yes, 2009
Abstrak. Hastuti D, Suranto, Setyono P. 2009. Variasi morfologi, karyotipe dan pola pita protein pada berbagai varietas kamboja jepang (Adenium obesum). Nusantara Bioscience 1: 78-83.
HASTUTI, DWI, SURANTO,, SETYONO, PRABANG
core   +1 more source

Cell Cycle Control of Nuclear Metabolism Couples Phosphatidylinositol Signaling to Histone Methylation

open access: yesAdvanced Science, EarlyView.
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater   +13 more
wiley   +1 more source

CHARACTERISATION OF IBD VIRAL PROTEINS IN SDS POLYACRYLAMIDE GEL ELECTROPHORESIS [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2004
The field isolates of IBD virus was characterised using protein profile study. Four structural polypeptides of IBD virus with molecular weights of 91 K (VP1), 39 K (VP,), 32 K (VP3), and 28 K (VP4) and the additional polypeptide 47 K (VPX) preceusor ...
M. Parthiban, V. Thiagarajan
doaj  

Mitochondrial protein import [PDF]

open access: yes, 1988
Transport of nuclear-encoded precursor proteins into mitochondria includes proteolytic cleavage of aminoterminal targeting sequences in the mitochondrial matrix. We have isolated the processing activity from Neurospora crassa.
Hartl, Franz-Ulrich   +5 more
core   +1 more source

GSH‐Responsive Nanoparticles Enhance Hepatocellular Carcinoma Immunotherapy Through Synergistic Effects of Cuproptosis and PI3K Inhibitor Combination

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cuproptosis, an emerging form of programmed cell death, is capable of inducing mitochondrial dysfunction. Moreover, the PI3K‐AKT‐mTOR signaling pathway contributes to tumor cell progression by reprogramming mitochondrial morphology and function.
Lei Wu   +10 more
wiley   +1 more source

Phosphoproteins and protein-kinase activity in isolated envelopes of pea (Pisum sativum L.) chloroplasts [PDF]

open access: yes, 1985
A protein kinase was found in envelope membranes of purified pea (Pisum sativum L.) chloroplasts. Separation of the two envelope membranes showed that most of the enzyme activity was localized in the outer envelope.
D.G. Robinson   +17 more
core   +1 more source

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