Tryptophan‐like dissolved organic matter (Try‐like DOM), a key component of organic matter in river ecosystems, demonstrates significant protective effects against plant viruses. The protective mechanism operates via a “swimming firewall” mode, whereby free Try‐like DOM attenuates ultraviolet (UV) radiation and scavenges reactive oxygen species ...
Yujie Wang+7 more
wiley +1 more source
Protein stabilization explains the gag requirement for transformation of lymphoid cells by Abelson murine leukemia virus [PDF]
The single protein encoded by Abelson murine leukemia virus is a fusion of sequence from the retroviral gag genes with the v-abl sequence. Deletion of most of the gag region from the transforming protein results in a virus capable of transforming ...
Baltimore, David+3 more
core
Disaggregation of adenylate cyclase during polyacrylamide-gel electrophoresis in mixtures of ionic and non-ionic detergents [PDF]
Andrew C. Newby, Andreas Chrambach
openalex +1 more source
This study reports an innovative strategy to improve the safety of OMVs by shielding them with a sophisticated shell composed of DaFe shell and Au nanoparticles, which not only reduces the toxicity of OMVs during circulation but also enables rapid release of these therapeutically active components in tumor for combined therapy involving glucose ...
Fan Zhang+11 more
wiley +1 more source
Characterization of Proteins from Nucleolar Preribosomes of Mouse Leukemia Cells by Two‐Dimensional Polyacrylamide Gel Electrophoresis [PDF]
Marie-Annick Auger-Buendia, M. Longuet
openalex +1 more source
LRRC4 deficiency disrupts the metabolic homeostasis of mitochondrial aerobic respiration and glycolysis during GC differentiation by inhibiting the ubiquitination‐mediated degradation of YAP, which ultimately leads to POI. These findings reveal the novel molecular etiology of POI and provide a promising target for prevention and treatment.
Yujie Shang+5 more
wiley +1 more source
DNA ladders can be used to size polyphosphate resolved by polyacrylamide gel electrophoresis. [PDF]
Smith SA, Wang Y, Morrissey JH.
europepmc +1 more source
CHARACTERIZATION OF BOAR SEMINAL PLASMA, VESICULAR SECRETION AND EPIDIDYMAL PLASMA PROTEINS BY GEL DISC ELECTROPHORESIS AND ISOELECTRIC FOCUSING ON POLYACRYLAMIDE [PDF]
U. Lavon, J. C. Boursnell
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This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang+5 more
wiley +1 more source
Controlling Dispersion during Single-Cell Polyacrylamide-Gel Electrophoresis in Open Microfluidic Devices. [PDF]
Pan Q, Yamauchi KA, Herr AE.
europepmc +1 more source