Results 131 to 140 of about 65,820 (278)

Variation and evolution of polyadenylation profiles in sauropsid mitochondrial mRNAs as deduced from the high-throughput RNA sequencing

open access: yesBMC Genomics, 2017
Background Genes encoded in vertebrate mitochondrial DNAs are transcribed as a polycistronic transcript for both strands, which is later processed into individual mRNAs, rRNAs and tRNAs, followed by modifications, such as polyadenylation at the 3′ end of
Yao Sun   +3 more
doaj   +1 more source

TAPAS: tool for alternative polyadenylation site analysis

open access: yesBioinform., 2018
Motivation: The length of the 3′ untranslated region (3′ UTR) of an mRNA is essential for many biological activities such as mRNA stability, sub‐cellular localization, protein translation, protein binding and translation efficiency. Moreover, correlation
Ashraful Arefeen   +3 more
semanticscholar   +1 more source

A Preliminary Association Study of H19 Non‐Coding Gene Variants With Risk of Non‐Hodgkin Lymphoma: A Case–Control Study and Computational Analysis

open access: yesJournal of Clinical Laboratory Analysis, Volume 39, Issue 11, June 2025.
Non‐Hodgkin lymphoma (NHL) is a kind of frequently occurring malignant tumor of the lymphoid hematopoietic system in the world. NHL comprises a large group of diverse lymphoid malignancies involving either the lymph nodes or extra nodal sites. It is more prevalent in males living in more developed countries over the age of 60 years.
Sara Kashani   +5 more
wiley   +1 more source

Ere, a Family of Short Interspersed Elements in the Genomes of Odd-Toed Ungulates (Perissodactyla)

open access: yesAnimals
Short Interspersed Elements (SINEs) are eukaryotic retrotransposons transcribed by RNA polymerase III (pol III). Many mammalian SINEs (T+ SINEs) contain a polyadenylation signal (AATAAA), a pol III transcription terminator, and an A-rich tail in their 3′-
Ilia G. Ustyantsev   +4 more
doaj   +1 more source

Phase Separation: A New Dimension to Understanding Tumor Biology and Therapy

open access: yesMedComm – Oncology, Volume 4, Issue 2, June 2025.
Liquid–liquid phase separation (LLPS) facilitates the assembly of biomolecular condensates by leveraging weak multivalent interactions. The low‐complexity domains, foldable domains of proteins, and nucleic acids provide multivalent interaction sites among different molecules and contribute to the formation of condensates.
Xingwen Wang   +4 more
wiley   +1 more source

CXXC5 is a ubiquitinated protein and is degraded by the ubiquitin‐proteasome pathway

open access: yesProtein Science, Volume 34, Issue 6, June 2025.
Abstract CXXC5, as a member of the zinc‐finger CXXC family proteins, interacts with unmodified CpG dinucleotides to modulate the expression of genes involved in cellular proliferation, differentiation, and death in physiology and pathophysiology. Various signaling pathways, including mitogenic 17β‐estradiol (E2), contribute to the expression and ...
Hazal Ayten   +10 more
wiley   +1 more source

piRNA processing within non‐membrane structures is governed by constituent proteins and their functional motifs

open access: yesThe FEBS Journal, Volume 292, Issue 11, Page 2715-2736, June 2025.
The silencing of transposable elements is mediated by piRNAs through post‐transcriptional and transcriptional regulation. In Drosophila, piRNAs are processed within unique non‐membrane structures: nuage in germline cells and Yb bodies in somatic gonadal cells.
Ritsuko Suyama, Toshie Kai
wiley   +1 more source

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