Results 161 to 170 of about 123,857 (304)

Sustainable Microwave‐Enhanced Synthesis of 2‐Substituted Benzofurans From o‐Alkynylanisoles in Acidic Deep Eutectic Solvents

European Journal of Organic Chemistry, EarlyView.
A microwave‐enhanced sustainable and versatile approach to substituted benzofurans from 2‐alkynylanisoles enabled by an active Brønsted acidic deep eutectic solvent. The research on alternative media for organic transformations remains a highly demanding topic.
Alessandra Gritti, Angelica Sita, Mehri Goudarzi, Stefano Fedeli, Elison Lepore, Donatella Nava, Matteo Tiecco, Alessandro Caselli, Valentina Pirovano, Giorgio Abbiati   +9 more
wiley   +1 more source

Modified Polycyclic Compounds Rescue Mis-splicing in Myotonic Dystrophy Type 1 Disease Models. [PDF]

ACS Chem Biol
Frias JA, Hicks SM, Mazdiyasni H, Mishra SK, Sarkar K, Yeboah C, LeFever NM, Scotti MM, Zeghal H, Brandt N, Vangaveti S, Chakma P, Wang T, Reid TS, McMichael O, Crumbaugh C, Provenzano M, Hale MA, Cleary JD, Johnson NE, Wang ET, Reddy K, Berglund JA.   +22 more
europepmc   +1 more source

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

European Journal of Organic Chemistry, EarlyView.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević, Ines Bašić, Mateja Matišić, Josip Rešetar, Matija Gredičak   +4 more
wiley   +1 more source

Glycine-Based [3+2] Cycloaddition for the Synthesis of Pyrrolidine-Containing Polycyclic Compounds. [PDF]

Molecules
Zhou T, Zhang X, Zhan D, Zhang W.
europepmc   +1 more source

Divergent Synthesis of Polycyclic Derivatives via Gold Catalysis

European Journal of Organic Chemistry, EarlyView.
Gold(I)‐catalyzed cycloisomerization enables the formation of complex 3D structures from simple enyne precursors. This study presents a divergent strategy to synthesize functionalized bicyclic and tricyclic scaffolds from a common alkynyl ketone.
Emilie Gentilini, Vincent Davenel, Pierre Ligonès, Jean‐Marie Fourquez, Véronique Michelet   +4 more
wiley   +1 more source

Synthesis and Structural and Optical Behavior of Dehydrohelicene-Containing Polycyclic Compounds. [PDF]

Molecules
Khalid MI, Salem MSH, Takizawa S.
europepmc   +1 more source

Design, Synthesis, and Photophysical Studies of Functionalized Polyaromatic Isonitriles as Visible Light Photoredox Catalysts

European Journal of Organic Chemistry, EarlyView.
A new series of structurally rich polyaromatic isonitriles is presented as photoredox catalysts. Their photophysical properties are investigated by UV–Vis absorption and fluorescence measurements, combined with experimental and theoretical studies to evaluate both ground‐ and excited‐state redox properties.
Cristina Martini, Camilla Russo, Jussara Amato, Carmine Volpe, Francesca Brunelli, Laurence Grimaud, Maxime R. Vitale, Greta Donati, Andrea Basso, Mariateresa Giustiniano   +9 more
wiley   +1 more source

Synthesis of π-conjugated polycyclic compounds by late-stage extrusion of chalcogen fragments. [PDF]

Beilstein J Org Chem
Okba A, Simón Marqués P, Matsuo K, Aratani N, Yamada H, Rapenne G, Kammerer C.   +6 more
europepmc   +1 more source

Unlocking the Functionalization and Reactivity of Ethylene Bridges in [2.2]Paracyclophanes: Strategies and Challenges

European Journal of Organic Chemistry, EarlyView.
Bridging the gap. Beyond deck functionalization, the ethylene bridges of [2.2]paracyclophanes offer a largely unexploited reactivity landscape. This review showcases strategies to functionalize these bridges and leverage them to build novel cyclophane architectures.
Rongyu Sun, Tamara Ye, Laurent Micouin, Erica Benedetti   +3 more
wiley   +1 more source

Biocatalytic strategy for the construction of sp³-rich polycyclic compounds from directed evolution and computational modelling. [PDF]

Nat Chem
Vargas DA, Ren X, Sengupta A, Zhu L, Roy S, Garcia-Borràs M, Houk KN, Fasan R.   +7 more
europepmc   +1 more source