Results 101 to 110 of about 25,511 (203)

Surgical cyst decortication in autosomal dominant polycystic kidney disease [PDF]

, 2013
PURPOSE: To provide a summary of the relevant literature regarding the impact of surgical cyst decortication on hypertension, renal function, and pain management in patients with autosomal dominant polycystic kidney disease (ADPKD).
Bhayani, Sam B, Clayman, Ralph V, Figenshau, R. Sherburne, Haseebuddin, Mohammed, Millar, Melissa, Tanagho, Youssef S   +5 more
core   +2 more sources

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

MedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu, Jiachen Liu, Yinhuai Wang, Fei Deng, Zebin Deng   +4 more
wiley   +1 more source

Results of kidney transplantation in patients with end-stage renal failure caused by autosomal dominant polycystic kidney disease

Вестник трансплантологии и искусственных органов, 2019
Aim. To investigate the renal transplantation results for patients with end-stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (PKD).Materials and methods.
V. S. Daineko, A. N. Ananiev, E. S. Nevirovich, A. E. Skvorcov, S. A. Budylev, А. N. Selivanov, M. M. Moskalenko, V. A. Manukovskiy, O. N. Reznik   +8 more
doaj   +1 more source

Renal ammonia in autosomal dominant polycystic kidney disease [PDF]

, 1994
Renal ammonia in autosomal dominant polycystic kidney disease. Recent studies have suggested that defective medullary trapping of ammonia underlies the acidosis associated with renal failure and sets in motion maladaptive compensatory mechanisms that ...
Agarwal, Alpern, Arruda, Bank, Batlle, Brenchley, Buerkert, Chapman, Clark, Cowley, Cowley, D'Angelo, David M. Wilson, de Jong, Denis, Donnelly, Dorhout-Mees, Douglas S. Keith, DuBose, DuBose, Elliot, Fine, Gabow, García Díaz, Gardner, Gardner, Gibson, Golchini, Grantham, Halliburton, Halperin, Halperin, Harrap, Hilton, Huseman, Ibels, Igarashi, Jacobsson, Kelly, Kenner, Kenneth P. Offord, Knepper, Knepper, Kriz, Levine, Liddle, Lotspeich, Maroni, Martinez-Maldonado, Martínez-Maldanado, Milutinovic, Morin, Nagami, Nagami, Natelson, Nath, Nath, Nath, Ogihara, Osterziel, Owen, Pabico, Plante, Preuss, Schmid, Simpson, Stern, Sui P. Kon, Thaysen, Tizianello, Tizianello, Tizianello, Tolins, Torres, Torres, Torres, Torres, Toyoda, Vicente E. Torres, Wilson, Wrong, Yu   +81 more
core   +1 more source

A Novel Inhibitor of Methyltransferase SMYD2, AZ505 Protects Against Peritoneal Fibrosis in Mice

Clinical and Experimental Pharmacology and Physiology, Volume 52, Issue 7, July 2025.
AZ505, a highly selective inhibitor of SMYD2, may exhibit an antifibrotic effect in peritoneal fibrosis. ABSTRACT AZ505, a highly selective inhibitor of SMYD2, exhibits an antifibrotic effect in renal fibrosis. Its effect on peritoneal fibrosis remains unexplored.
Taijing Xu, Binbin Cui, Feng Liu, Mengjun Liu, Xiying Hou, Xuan Hong, Hualin Qi   +6 more
wiley   +1 more source

Autosomal dominant polycystic kidney disease: updated perspectives

Therapeutics and Clinical Risk Management, 2019
Anjay Rastogi,1 Khalid Mohammed Ameen,1 Maha Al-Baghdadi,1 Kelly Shaffer,1 Niloofar Nobakht,1 Mohammad Kamgar,1 Edgar V Lerma21Department of Medicine, Division of Nephrology, David Geffen School of Medicine, Los Angeles, CA, USA; 2Department of Medicine,
Rastogi A, Ameen KM, Al-Baghdadi M, Shaffer K, Nobakht N, Kamgar M, Lerma EV   +6 more
doaj  

Renin-Angiotensin-Aldosterone System Antagonism and Polycystic Kidney Disease Progression. [PDF]

, 2016
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a systemic disease characterised by the formation of multiple renal cysts that adversely affect renal function.
Hian, Chuan Kai, Lee, Chin Liang, Thomas, Warren   +2 more
core   +2 more sources

Human asthenozoospermia: Update on genetic causes, patient management, and clinical strategies

Andrology, Volume 13, Issue 5, Page 1044-1064, July 2025.
Abstract Background In mammals, sperm fertilization potential relies on efficient progression within the female genital tract to reach and fertilize the oocyte. This fundamental property is supported by the flagellum, an evolutionarily conserved organelle, which contains dynein motor proteins that provide the mechanical force for sperm propulsion and ...
Emma Cavarocchi, Maëva Drouault, Joao C. Ribeiro, Violaine Simon, Marjorie Whitfield, Aminata Touré   +5 more
wiley   +1 more source

Renal Transplantation in Autosomal Dominant Polycystic Kidney Disease [PDF]

European Medical Journal Nephrology, 2015
Autosomal dominant polycystic kidney disease (ADPKD) affects approximately 1 in 1,000 people in the general population. The natural history of ADPKD includes the progression of chronic kidney disease to end-stage renal disease (ESRD) in a large ...
Andrzej Kulesza, Longin Niemczyk, Mariusz Niemczyk   +2 more
doaj  

Epigenetics and autosomal dominant polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011
The roles of epigenetic modulation of gene expression and protein functions in autosomal dominant polycystic kidney disease (ADPKD) have recently become the focus of scientific investigation. Evidence generated to date indicates that one of the epigenetic modifiers, histone deacetylases (HDACs), are important regulators of ADPKD.
openaire   +3 more sources