Results 81 to 90 of about 4,269 (127)
Targeting TRPM3 As a Potential Therapeutic Approach for Autosomal Dominant Polycystic Kidney Disease
Cystic diseases, especially autosomal dominant polycystic kidney disease (ADPKD; incidence approx. 1/1000), are a leading cause of renal failure, caused by appearance and growth of renal cysts that can lead to renal failure in middle age.
Gul, Huseyin
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Blood pressure in early autosomal dominant polycystic kidney disease
BACKGROUND Hypertension is common in autosomal dominant polycystic kidney disease (ADPKD) and is associated with increased total kidney volume, activation of the renin-angiotensin- aldosterone system, and progression of kidney disease ...
Winklhofer, Franz T. +17 more
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TRPP2 and autosomal dominant polycystic kidney disease
Mutations in TRPP2 (polycystin-2) cause autosomal dominant polycystic kidney disease (ADPKD), a common genetic disorder characterized by progressive development of fluid-filled cysts in the kidney and other organs. TRPP2 is a Ca(2+)-permeable nonselective cation channel that displays an amazing functional versatility at the cellular level.
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Long-term trajectory of kidney function in autosomal-dominant polycystic kidney disease
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by cyst and kidney growth, which is hypothesized to cause loss of functioning renal mass and eventually end-stage kidney disease.
Rahbari-Oskoui, Frederic F. +25 more
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Autosomal dominant polycystic kidney disease [PDF]
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Steven M Brunelli,1 Christopher M Blanchette,2,3 Ami J Claxton,1 Debosree Roy,2 Sandro Rossetti,3 Benjamin Gutierrez31DaVita Clinical Research, Minneapolis, MN, USA; 2University of North Carolina, Charlotte, NC, USA; 3Otsuka America Pharmaceutical, Inc.,
Claxton AJ +5 more
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Kidney transplantation is the treatment of choice for many individuals with end stage renal disease (ESRD), as transplantation is reported to offer a greater quality of life than renal dialysis.
Long-Sutehall, Tracy +4 more
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Tolvaptan in Autosomal Dominant Polycystic Kidney Disease [PDF]
Vicente E, Torres +2 more
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Autosomal dominant polycystic kidney disease.
Schwenger Vedat, Zeier Martin
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Hypertension in autosomal dominant polycystic kidney disease.
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