Results 71 to 80 of about 4,269 (127)

[Hypophyseal incidentaloma in a patient with autosomal dominant polycystic kidney disease]

, 2002
The prevalence of incidentally discovered lesions within the pituitary (pituitary incidentalomas) is about 10%. The most common form of sellar mass are clinically nonfunctioning adenomas (less than 10 mm); functioning adenomas, however, are rare ...
Fajfr, R, Diem, P, Müller, B
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Progression of autosomal dominant kidney disease: measurement of the stage transitions of chronic kidney disease

, 2015
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a progressive genetic disorder characterized by the development of numerous kidney cysts that result in kidney failure.
Nancy Lin, Xiangmei Gu, Christopher M Blanchette, Britt Newsome, Deborah Lubeck, Sandro Rossetti, Benjamin Gutierrez, Caihua Liang, Deborah P Lubeck, Ciahua Liang, Sandro Rossett, Christopher Blanchette, Nancy D Lin   +12 more
core   +1 more source

Epigenetics and autosomal dominant polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011
The roles of epigenetic modulation of gene expression and protein functions in autosomal dominant polycystic kidney disease (ADPKD) have recently become the focus of scientific investigation. Evidence generated to date indicates that one of the epigenetic modifiers, histone deacetylases (HDACs), are important regulators of ADPKD.
openaire   +2 more sources

Autosomal-dominant polycystic kidney disease in the rat

Kidney International, 1993
Kaspareit-Rittinghausen described a rodent model of inherited polycystic kidney disease (PKD), the Han:SPRD rat [1, 2], in which heterozygotes develop renal cysts and renal failure (in males) over several months, whereas homozygous animals develop rapidly progressive renal enlargement that leads to death in a few weeks.
Cowley, Benjamin D., Gudapaty, Seshagirirao, Kraybill, Amy L., Barash, Brian D., Harding, Michael A., Calvet, James P., Gattone, Vincent H.   +6 more
openaire   +2 more sources

Treatment prospects for autosomal-dominant polycystic kidney disease

, 2001
Treatment prospects for autosomal-dominant polycystic kidney disease. An increased understanding of the molecular genetic and cellular pathophysiologic mechanisms responsible for the development of autosomal-dominant polycystic kidney disease (ADPKD ...
Harris, Peter C., Torres, Vicente E., Qian, Qi   +2 more
core   +1 more source

Relevance of ultrasound examination in general practice. A case report of a patient with autosomal dominant polycystic kidney disease

, 2013
Autosomal dominant polycystic kidney disease is a genetic disorder which results in the development of multiple cysts in the kidneys and other parenchymal organs. The two genes in which mutations are known to cause autosomal dominant polycystic kidney
Izabela Cwojdzińska-Jankowska, Cwojdzińska-Jankowska, Izabela, Anna Plewa, Plewa, Anna   +3 more
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Rationale and design of the TEMPO (Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and its Outcomes) 3-4 Study.

, 2011
Current management of autosomal dominant polycystic kidney disease (ADPKD) is focused on treating disease complications, not on slowing cyst development or preventing progression to kidney failure.
Grantham, Jared J., Vicente E. Torres, Torres, Vicente E., Meijer, Esther, Eiji Higashihara, Kyongtae T. Bae, Olivier Devuyst, Ronald D. Perrone, Chapman, Arlene B., Krasa, Holly B., Higashihara, Eiji, John J. Ouyang, Perrone, Ronald D., Esther Meijer, Ouyang, John J., Bae, Kyongtae T., Jared J. Grantham, Arlene B. Chapman, Devuyst, Olivier, Ron T. Gansevoort, Gansevoort, Ron T., Czerwiec, Frank S., Holly B. Krasa, Frank S. Czerwiec   +23 more
core   +1 more source

Autosomal Dominant Polycystic Kidney Disease: What Do We Need To Know For Counselling?

, 2014
In the new millennium, few kidney diseases changed their perspectives as much as autosomal dominant polycystic kidney disease (ADPKD). New diagnostic approaches, including the evaluation of renal or liver volume by computerised tomography (CT) scan, the ...
Federica Solitro, Giorgina Barbara Piccoli, Vincenzo Arena, Rossella Attini, Andrea Veltri, Agostino De Pascale, Federica Neve Vigotti, Anna Pia, Roberta Clari, Gabriella Guzzo   +9 more
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Long-term safety profile of tolvaptan in autosomal dominant polycystic kidney disease patients: TEMPO Extension Japan Trial

, 2017
Satoru Muto,1 Tadashi Okada,2 Moriyoshi Yasuda,3 Hidetsugu Tsubouchi,4 Koji Nakajima,4 Shigeo Horie1,5 1Department of Advanced Informatics for Genetic Disease, Juntendo University Graduate School of Medicine, Tokyo, 2Department of Clinical Development ...
Nakajima K, Yasuda M, Horie S, Muto S, Tsubouchi H, Okada T   +5 more
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Autosomal dominant polycystic kidney disease

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a diagnosis typically made following imaging of the renal tract. The characteristic features of enlarged bilateral polycystic kidneys with or without liver cysts and a positive family history allow ...
Richard Sandford
core   +1 more source