Results 171 to 180 of about 488,068 (360)

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Tolvaptan in patients with autosomal dominant polycystic kidney disease.

open access: yesNew England Journal of Medicine, 2012
V. Torres   +9 more
semanticscholar   +1 more source

Therapeutic Potential of Resveratrol in Cancer and Neurodegenerative Disorders: A Current Review

open access: yesBioFactors, Volume 52, Issue 1, January/February 2026.
Resveratrol induces the expressions of TP53, NRF2, and JDP2 axis in cancer cells to control ROS balance in mitochondria. The antioxidation responses were induced through SRIT1/3, HDAC, STAT3, TGFβ, and so on, to trigger the inflammation, and NFkB response to lead to the cell death of cancers or neuro‐damaged cells.
Kenly Wuputra   +9 more
wiley   +1 more source

Association Discovery Approach in Healthcare Big Data to Identify Drug Safety and Drug Repurposing Signals

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.
Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan   +6 more
wiley   +1 more source

Earlier Menopause and Risk of Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Global Cohort Study

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 1, January 2026.
ABSTRACT Objectives Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a growing public health concern that contributes to liver and cardiovascular complications. The prevalence of MASLD in women increases sharply around age 50 years, but the relationship between an earlier age at natural menopause and MASLD is unknown.
Joshua Stokar, Rivka Dresner‐Pollak
wiley   +1 more source

The Combined Effects of an Anti‐Inflammatory Diet and Curcumin Supplementation on Thyroid Function and Lipid Profile in Patients With Hashimoto's Thyroiditis: A Double Blind Randomised Clinical Trial

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Anti‐TPO levels, along with waist circumference and waist‐to‐hip ratio, showed notable reductions in the curcumin group compared to placebo, while other thyroid‐related and metabolic markers remained largely unchanged. ABSTRACT Background Hashimoto's thyroiditis (HT) is an inflammatory autoimmune disease and patients with HT may benefit from ...
Fatemeh Bourbour   +6 more
wiley   +1 more source

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