Results 181 to 190 of about 46,408 (230)

Inferior Vena Cava Thrombosis After Nephrectomy of the Native Kidneys in Patients With Autosomal Dominant Polycystic Kidney Disease. [PDF]

open access: yesIJU Case Rep
Matsushita Y   +9 more
europepmc   +1 more source

Kynurenines in polycystic kidney disease

Journal of Nephrology, 2022
Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder, characterized by kidney cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation.
Jost, Klawitter   +8 more
openaire   +2 more sources

Polycystic Kidney Disease

Comprehensive Physiology, 2017
ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
openaire   +2 more sources

Cilia and polycystic kidney disease

Seminars in Cell & Developmental Biology, 2021
Polycystic kidney disease (PKD), comprising autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), is characterized by incessant cyst formation in the kidney and liver. ADPKD and ARPKD represent the leading genetic causes of renal disease in adults and children, respectively.
openaire   +2 more sources

Polycystic Kidney Disease

New England Journal of Medicine, 2004
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
openaire   +2 more sources

Reversing polycystic kidney disease

Nature Genetics, 2021
A new study shows that re-expressing PKD genes early in the course of the disease can fully reverse polycystic kidney disease in mice. These results reveal an unexpected ability of the kidney to regenerate following genetic rescue of polycystin function.
openaire   +2 more sources

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