Results 181 to 190 of about 53,957 (281)

Polycystic Kidney Disease

, 2019
Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are two forms of polycystic kidney disease (PKD) and are leading causes of end stage renal disease (Silverman, 2015).
Byrne, Caitlin
core  

The impact of breast milk relaxin 2, oxytocin, and insulin‐like peptide 3 on neonatal growth parameters in early life

Journal of Pediatric Gastroenterology and Nutrition, Volume 82, Issue 6, Page 1479-1487, June 2026.
Abstract Objectives This study aims to quantify the levels of relaxin 2 (RLX2), oxytocin (OXT), and insulin‐like peptide 3 (INSL3) in colostrum (postpartum days 1–5, Visit 1) and mature breast milk (postpartum days 21–35, Visit 2), and to evaluate their associations with neonatal growth outcomes.
Hakan Doneray, Ayse Ozden, Guzide Tavlas, Halil Ibrahim Ozkan   +3 more
wiley   +1 more source

Bone Phenotype in Autosomal Dominant Polycystic Kidney Disease. [PDF]

Calcif Tissue Int
Jankowska M, Magnusson P, Debowska M, Lindholm B, Qureshi AR, Lukaszuk T, Dębska-Ślizień A, Fuster DG, Stenvinkel P, Haarhaus M.   +9 more
europepmc   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

SGLT2 Inhibitors in Autosomal Dominant Polycystic Kidney Disease: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Tantush A, Ben Hamida B, Sagher M, Afsheen N, Sager M, Abusbaeh A, Tantoush M, Abusbaeh A, Najaim A, Alhamadi M, Hesham Gamal M, Alemam MM, Elhady MM.   +12 more
europepmc   +1 more source

Protein Tyrosine Phosphatase 1B‐Mediated Granulosa Cell Insulin Resistance Links Metabolic Stress to Aging‐Relevant Ovarian Dysfunction and Is Reversed by Gengnianchun

Aging Cell, Volume 25, Issue 6, June 2026.
Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao, Ting Xu, Yan Ding, Jun Li, Lingyun Gao, Yun Wang, Wenjun Wang   +6 more
wiley   +1 more source

Progressive endocannabinoid system dysregulation in autosomal dominant polycystic kidney disease. [PDF]

Mol Med
Betkar S, Nemirovski A, Ruppo S, Hinden L, Tam J.   +4 more
europepmc   +1 more source

End-stage renal disease in autosomal dominant polycystic kidney disease: a comparison of dialysis-related utilization and costs with other chronic kidney diseases

, 2015
Steven M Brunelli,1 Christopher M Blanchette,2,3 Ami J Claxton,1 Debosree Roy,2 Sandro Rossetti,3 Benjamin Gutierrez31DaVita Clinical Research, Minneapolis, MN, USA; 2University of North Carolina, Charlotte, NC, USA; 3Otsuka America Pharmaceutical, Inc.,
Claxton AJ, Blanchette CM, Roy D, Brunelli SM, Gutierrez B, Rossetti S   +5 more
core  

Outcomes Following Alemtuzumab Induction in Deceased Donor Kidney Transplantation According to Recipient Age Categories: A Single Center Report

Clinical Transplantation, Volume 40, Issue 6, June 2026.
ABSTRACT Introduction The effects of induction therapy with the anti‐CD52 monoclonal antibody alemtuzumab on age‐specific outcomes following kidney transplantation (KT) remain inadequately studied. This study aimed to analyze the comparative safety and efficacy of single‐dose alemtuzumab induction in deceased donor (DD) KT recipients according to ...
Alex Ng, David I. Harriman, Alan C. Farney, Giuseppe Orlando, Colleen Jay, Amber Reeves‐Daniel, Robert J. Stratta   +6 more
wiley   +1 more source

Macroscopic hematuria in children with autosomal dominant polycystic kidney disease - report from four European tertiary centers. [PDF]

Eur J Pediatr
Seeman T, Bláhová K, Fencl F, John-Kroegel U, Weigel F, Šuláková T, Podracká L, Feber J.   +7 more
europepmc   +1 more source