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Coincidence of autosomal dominant polycystic kidney disease and Alport syndrome: a case report and literature review. [PDF]
Liu R, Liu F.
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Machine Learning Prediction of Progression to Dialysis in Patients With Polycystic Kidney Disease: Population-Based Retrospective Cohort Study. [PDF]
Chang CH +7 more
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Inferior Vena Cava Thrombosis After Nephrectomy of the Native Kidneys in Patients With Autosomal Dominant Polycystic Kidney Disease. [PDF]
Matsushita Y +9 more
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Kynurenines in polycystic kidney disease
Journal of Nephrology, 2022Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder, characterized by kidney cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation.
Jost, Klawitter +8 more
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Comprehensive Physiology, 2017
ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
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ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
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Cilia and polycystic kidney disease
Seminars in Cell & Developmental Biology, 2021Polycystic kidney disease (PKD), comprising autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), is characterized by incessant cyst formation in the kidney and liver. ADPKD and ARPKD represent the leading genetic causes of renal disease in adults and children, respectively.
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New England Journal of Medicine, 2004
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
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Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
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Reversing polycystic kidney disease
Nature Genetics, 2021A new study shows that re-expressing PKD genes early in the course of the disease can fully reverse polycystic kidney disease in mice. These results reveal an unexpected ability of the kidney to regenerate following genetic rescue of polycystin function.
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