Results 211 to 220 of about 53,957 (281)

HIF‐Regulated Pannexin‐1 Channel Drives Luminal ATP Accumulation in Kidney Cysts

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Autosomal dominant polycystic kidney disease causes progressive cyst enlargement in the kidneys, leading to hypoxia and induction of HIF‐1α. Our study identifies HIF‐1α‐dependent transcriptional upregulation of Pannexin1 (PANX1) in the apical membrane of cyst epithelial cells, promoting ATP release into the cyst lumen.
Kathrin Skoczynski, Julia Katharina Scholz, Raluca Ursu, Johannes Schödel, Steffen Grampp, Stephanie Naas, Victoria Lauer, Mario Schiffer, Maike Büttner‐Herold, Bjoern Buchholz, Andre Kraus   +10 more
wiley   +1 more source

Pellino1-mTOR/S6K1 signaling axis is a key pathogenesis for the development of polycystic kidney disease. [PDF]

Cell Death Dis
Kim S, Kim MH, Ko BK, Kim KM, Wang N, Jo SM, Go H, Park EJ, Lee CW.   +8 more
europepmc   +1 more source

Pierson syndrome with numerous dilated tubules masquerading as autosomal recessive polycystic kidney disease: a case report. [PDF]

CEN Case Rep
Yamamura-Miyazaki N, Michigami T, Okamoto N, Iida T, Yanagi K, Kaname T, Fukuda S, Baba M, Fujiwara K, Kubota T.   +9 more
europepmc   +1 more source

A case of autosomal dominant polycystic kidney disease with multiple bilateral spontaneous retroperitoneal hemorrhages. [PDF]

CEN Case Rep
Mizuta M, Suwabe T, Oba Y, Sekine A, Yamanouchi M, Mizuno H, Hasegawa E, Wada T, Fukuda M, Miyazono M, Sawa N, Ubara Y.   +11 more
europepmc   +1 more source

Inhibition of the inflammasome ameliorates orthologous polycystic kidney disease. [PDF]

Proc Natl Acad Sci U S A
Liu J, Rogg M, Moos K, Sasanpour S, Strassl V, Jain M, Magassa S, Neubauer B, Braeg S, Saller BS, Weißer L, Bienaimé F, Gorka O, Boerries M, Viau A, Gross O, Schell C, Kuehn EW.   +17 more
europepmc   +1 more source

Renal Disease Burden in Prurigo Nodularis: A Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 6, Page 1238-1245, June 2026.
Natalia Chalupczak, Natalie Bourand, Deborah Woo, Raj Chovatiya   +3 more
wiley   +1 more source

Epithelial Dynamics of Cystogenesis in Genetic Models of Autosomal Dominant Polycystic Kidney Disease. [PDF]

Cells
Sun M, Wu Z, Hu M, Luo W, Chen X, Ma M.
europepmc   +1 more source

Role of Mediterranean Diet Adherence on Endothelial Dysfunction in Autosomal Dominant Polycystic Kidney Disease Patients. [PDF]

Biomolecules
Salomone L, Menichelli D, Cammisotto V, Castellani V, Pastori D, Pignatelli P, Mitterhofer AP, Tinti F, Lai S.   +8 more
europepmc   +1 more source

Association of 24-hour urinary parameters with renal function and other comorbidities in autosomal dominant polycystic kidney disease. [PDF]

BMC Nephrol
Aykut H, Alışır Ecder S, Ecder T.
europepmc   +1 more source

Correction: Lack of ANKMY2 suppresses kidney cystogenesis in embryonic- and adult-onset polycystic kidney disease. [PDF]

PLoS Genet
PLOS Genetics Staff.
europepmc   +1 more source