Results 221 to 230 of about 462,629 (365)

Polycystin 2 is increased in disease to protect against stress-induced cell death [PDF]

, 2020
Brill, Allison L., Campbell, Stuart G., Cantley, Lloyd G., Chung, Hee Jung, Ehrlich, Barbara E., Fischer, Tom T., Johnson, Eric K., Marlier, Arnaud, Moeckel, Gilbert, Nerbonne, Jeanne M., Robert, Marie E., Sewanan, Lorenzo R., Walters, Jennifer M., Wilson, Parker C.   +13 more
core   +1 more source

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

MedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar, Sana Khurshid Baba, Inamu Rashid Khan, Mohd Shahnawaz Khan, Fohad Mabood Husain, Saheem Ahmad, Mohammad Haris, Mayank Singh, Ammira S. Al‐Shabeeb Akil, Muzafar A. Macha, Ajaz A. Bhat   +10 more
wiley   +1 more source

Analysis of a large family with the second type of autosomal dominant polycystic kidney disease [PDF]

, 1996
Barbera Veldhuisen, M.H. Breuning, Eveline Wesby–van Swaay, J. Boersma, Dorien J.M. Peters   +4 more
openalex   +1 more source

Screening for intracranial aneurysms in ADPKD [PDF]

, 2009
Ong, A.C.M.
core   +1 more source

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

MedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu, Jiachen Liu, Yinhuai Wang, Fei Deng, Zebin Deng   +4 more
wiley   +1 more source

Life table analysis of feline polycystic kidney disease in Japan. [PDF]

J Vet Med Sci
Enomoto T, Kobayashi S, Ishiguro N.
europepmc   +1 more source

Organic anion secretion in polycystic kidney disease. [PDF]

, 1997
George A. Tanner, N. Gretz, Yi Ming Shao, Andrew P. Evan, M Steinhausen   +4 more
openalex   +1 more source

Fluorinated Zirconium‐Based Metal‐Organic Frameworks as Novel Sorbents to Improve the Efficacy of Hemodialysis Treatment

Small Science, Volume 5, Issue 7, July 2025.
The incorporation of perfluoroalkyl chains into porous NU‐1000 leads to superior performance in the removal of uremic toxins from samples of CKD patients for two main reasons: improved stability and enhanced removal efficiency of protein‐bound toxins.
Fátima Guerrero, Francisco G. Moscoso, Joaquín Silvestre‐Albero, Alejandro Martin‐Malo, Carolina Carrillo‐Carrión   +4 more
wiley   +1 more source

A Novel Inhibitor of Methyltransferase SMYD2, AZ505 Protects Against Peritoneal Fibrosis in Mice

Clinical and Experimental Pharmacology and Physiology, Volume 52, Issue 7, July 2025.
AZ505, a highly selective inhibitor of SMYD2, may exhibit an antifibrotic effect in peritoneal fibrosis. ABSTRACT AZ505, a highly selective inhibitor of SMYD2, exhibits an antifibrotic effect in renal fibrosis. Its effect on peritoneal fibrosis remains unexplored.
Taijing Xu, Binbin Cui, Feng Liu, Mengjun Liu, Xiying Hou, Xuan Hong, Hualin Qi   +6 more
wiley   +1 more source

Ciliary Ion Channels in Polycystic Kidney Disease. [PDF]

Cells
Alshriem LA, Buqaileh R, Alorjani Q, AbouAlaiwi W.   +3 more
europepmc   +1 more source