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The FASEB Journal, Volume 39, Issue 10, 31 May 2025.SMYD2 mediates the activation of the NF‐κB signaling pathway to promote cisplatin‐induced chronic kidney injury. Cisplatin stimulation induces the upregulation of SMYD2 expression in renal tubular epithelial cells. SMYD2 promotes the phosphorylation of the p65 subunit of NF‐κB through methylation, thereby facilitating the release of inflammatory ...
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