Results 31 to 40 of about 462,629 (365)

Combined liver-kidney transplant in polycystic diseases: a case report [PDF]

Einstein (São Paulo), 2023
Polycystic liver disease, a hereditary pathology, usually manifests as autosomal dominant polycystic kidney disease. The many cysts in the liver cause massive hepatomegaly, majorly affecting the patient’s quality of life. In cases of refractory symptoms,
Olival Cirilo Lucena da Fonseca Neto, Beatriz Costa Nava Martins, Norma Thomé Jucá, Victor Cruz Rosa Alencar de Sá, Priscylla Jennie Monteiro Rabêlo, Paulo Sérgio Vieira de Melo, Américo Gusmão Amorim, Cláudio Moura Lacerda   +7 more
doaj   +1 more source

Beyond polycystic kidney disease [PDF]

BMJ Case Reports, 2017
Tuberous sclerosis(TS) is an autosomal dominant disease caused by mutations inTSC1andTSC2genes.TSC2gene is located in chromosome 16p13.3, adjacent toPKD1gene, responsible for the autosomal dominant polycystic kidney disease. In a rare subgroup of patients, the presence of a deletion which simultaneously affects theTSC2andPKD1genes has been confirmed ...
Santos, SF, Francisco, T, Cordeiro, AI, Lopes, MJ   +3 more
openaire   +4 more sources

Improved Structure and Function in Autosomal Recessive Polycystic Rat Kidneys with Renal Tubular Cell Therapy. [PDF]

PLoS ONE, 2015
Autosomal recessive polycystic kidney disease is a truly catastrophic monogenetic disease, causing death and end stage renal disease in neonates and children.
K J Kelly, Jizhong Zhang, Ling Han, Malgorzata Kamocka, Caroline Miller, Vincent H Gattone, Jesus H Dominguez   +6 more
doaj   +1 more source

Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease [PDF]

, 2016
The neurohypophysial hormone arginine vasopressin (AVP) acts by three distinct receptor subtypes: V1a, V1b, and V2. In the liver, AVP is involved in ureogenesis, glycogenolysis, neoglucogenesis and regeneration. No data exist about the presence of AVP in
Alpini, Gianfranco, Carpino, Guido, Franchitto, Antonio, Gaudio, Eugenio, Glaser, Shannon, Mancinelli, Romina, Olivero, Francesca, Onori, Paolo, Pannarale, Luigi, Sferra, Roberta, Venter, Julie, Vetuschi, Antonella   +11 more
core   +1 more source

Molecular Mechanisms of Isolated Polycystic Liver Diseases

Frontiers in Genetics, 2022
Polycystic liver disease (PLD) is a rare autosomal dominant disorder including two genetically and clinically distinct forms: autosomal dominant polycystic kidney disease (ADPKD) and isolated polycystic liver disease (PCLD).
Ziqi Yu, Xiang Shen, Chong Hu, Jun Zeng, Aiyao Wang, Jianyong Chen   +5 more
doaj   +1 more source

Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology-Polycystic Kidney Disease (SONG-PKD) Consensus Workshop.

American Journal of Kidney Diseases, 2020
The omission of outcomes that are of relevance to patients, clinicians and regulators across trials in autosomal dominant polycystic kidney disease (ADPKD) limits shared decision-making. The Standardized Outcomes in Nephrology - Polycystic Kidney Disease
Yeoungjee Cho, A. Tong, J. Craig, R. Mustafa, A. Chapman, R. Perrone, C. Ahn, K. Fowler, V. Torres, R. Gansevoort, A. Ong, Helen Coolican, Juliana Tze-Wah Kao, T. Harris, Talia Gutman, Jenny I. Shen, A. Viecelli, David W. Johnson, E. Au, R. El-Damanawi, C. Logeman, A. Ju, Karine E. Manera, M. Chonchol, Dwight Odland, David A. Baron, Y. Pei, B. Sautenet, A. Rastogi, Ankit Sharma, G. Rangan   +30 more
semanticscholar   +1 more source

MicroRNAs and Polycystic Kidney Disease [PDF]

Drug Discovery Today: Disease Models, 2013
Polycystic kidney disease (PKD), the most common genetic cause of chronic renal failure, is characterized by the presence of numerous fluid-filled cysts in renal parenchyma. Despite recent progress, no FDA-approved therapy is available to retard cyst growth.
Ronak Lakhia, Vishal Patel, Sachin Hajarnis   +2 more
openaire   +4 more sources

Magnetic resonance imaging 3t and total fibrotic volume in autosomal dominant polycystic kidney disease [PDF]

, 2018
INTRODUCTION: Autosomal dominant polycystic kidney disease (ADPKD) is the most common renal hereditary disorder. Several authors have attempted to identify a kidney damage marker for predicting the prognosis and the effectiveness of therapy in ADPKD ...
Ciccariello, Mauro, D'Angelo, Anna Rita, DI GAETA, Alessandro, Ferrigno, Luigina, Lai, Silvia, Letizia, Claudio, Mastroluca, Daniela, Panebianco, Valeria, Perrotta, ADOLFO MARCO, Petramala, Luigi   +9 more
core   +1 more source

Participant Perceptions in a Long-term Clinical Trial of Autosomal Dominant Polycystic Kidney Disease

Kidney Medicine, 2023
Rationale & Objective: The development of new therapies for autosomal dominant polycystic kidney disease requires clinical trials to be conducted efficiently. In this study, the factors affecting the recruitment and retention of participants enrolled
Sneha Amin, Irene Sangadi, Margaret Allman-Farinelli, Sunil V. Badve, Neil Boudville, Helen Coolican, Susan Coulshed, Sheryl Foster, Mangalee Fernando, Imad Haloob, David C.H. Harris, Carmel M. Hawley, Jane Holt, Martin Howell, Karthik Kumar, David W. Johnson, Vincent W. Lee, Jun Mai, Anna Rangan, Simon D. Roger, Kamal Sud, Vicente Torres, Eswari Vilayur, Gopala K. Rangan   +23 more
doaj  

Surgical Management of Autosomal Dominant Polycystic Kidney Disease: Principles and Current Practice

Journal of Nepal Medical Association, 2023
Autosomal dominant polycystic kidney disease is the third most common cause of renal failure with no definitive treatment available that can directly target the development and growth of the cysts.
Badri Man Shrestha
doaj   +1 more source