Results 41 to 50 of about 488,068 (360)

Molecular Mechanisms of Isolated Polycystic Liver Diseases

Frontiers in Genetics, 2022
Polycystic liver disease (PLD) is a rare autosomal dominant disorder including two genetically and clinically distinct forms: autosomal dominant polycystic kidney disease (ADPKD) and isolated polycystic liver disease (PCLD).
Ziqi Yu, Xiang Shen, Chong Hu, Jun Zeng, Aiyao Wang, Jianyong Chen   +5 more
doaj   +1 more source

Urinary proteomics using capillary electrophoresis coupled to mass spectrometry for diagnosis and prognosis in kidney diseases [PDF]

, 2016
Purpose of review: Urine is the most useful of body fluids for biomarker research. Therefore, we have focused on urinary proteomics, using capillary electrophoresis coupled to mass spectrometry, to investigate kidney diseases in recent years.
Magalhães, Pedro, Mischak, Harald, Zürbig, Petra   +2 more
core   +1 more source

International consensus statement on the diagnosis and management of autosomal dominant polycystic kidney disease in children and young people

Nature Reviews Nephrology, 2019
These recommendations were systematically developed on behalf of the Network for Early Onset Cystic Kidney Disease (NEOCYST) by an international group of experts in autosomal dominant polycystic kidney disease (ADPKD) from paediatric and adult nephrology,
C. Gimpel, C. Bergmann, D. Bockenhauer, L. Breysem, M. Cadnapaphornchai, M. Cetiner, J. Dudley, F. Emma, M. Konrad, T. Harris, P. Harris, J. König, M. Liebau, M. Marlais, D. Mekahli, A. M. Metcalfe, Jun Oh, R. Perrone, M. Sinha, A. Titieni, R. Torra, S. Weber, P. Winyard, F. Schaefer   +23 more
semanticscholar   +1 more source

Inverting the patient involvement paradigm: defining patient led research

Research Involvement and Engagement, 2018
Plain English Summary Patients usually understand their disease and lifestyle needs better than many medical professionals. They also have important ideas about what research would be most beneficial to their lives, especially on how to manage symptoms ...
Laura B. Mader, Tess Harris, Sabine Kläger, Ian B. Wilkinson, Thomas F. Hiemstra   +4 more
doaj   +1 more source

Surgical Management of Autosomal Dominant Polycystic Kidney Disease: Principles and Current Practice

Journal of Nepal Medical Association, 2023
Autosomal dominant polycystic kidney disease is the third most common cause of renal failure with no definitive treatment available that can directly target the development and growth of the cysts.
Badri Man Shrestha
doaj   +1 more source

Effect of ovariectomy on the progression of chronic kidney disease-mineral bone disorder (CKD-MBD) in female Cy/+ rats [PDF]

, 2019
Male Cy/+ rats have shown a relatively consistent pattern of progressive kidney disease development that displays multiple key features of late stage chronic kidney disease-mineral bone disorder (CKD-MBD), specifically the development of cortical bone ...
Allen, Matthew R., Chen, Neal X., Hill Gallant, Kathleen M., Lachcik, Pamela J., Metzger, Corinne E., Moe, Sharon M., Swallow, Elizabeth A., Vorland, Colby J.   +7 more
core   +1 more source

Aberrant Polycystin-1 Expression Results in Modification of Activator Protein-1 Activity, whereas Wnt Signaling Remains Unaffected [PDF]

, 2004
Polycystin-1, the polycystic kidney disease 1 gene product, has been implicated in several signaling complexes that are known to regulate essential cellular functions. We investigated the role of polycystin-1 in Wnt signaling and activator protein-1 (
Arnould, Bhunia, Duyndam, Giles, Grotewold, Huan, Kim, Kimberling, Kugoh, Loghman-Adham, Löhning, Morin, Moser, Muto, Newby, Ouwens, Parnell, Peters, Pritchard, Rivat, Rodova, Saadi-Kheddouci, Scheffers, Shaulian, Smits, Sorenson, Spaargaren, Streets, Sutters, Trudel, Upadhya, van Adelsberg, van Dam, van Dam, van Dam, van Dam, van de Wetering, van de Wetering   +37 more
core   +3 more sources

Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology-Polycystic Kidney Disease (SONG-PKD) Consensus Workshop.

American Journal of Kidney Diseases, 2020
The omission of outcomes that are of relevance to patients, clinicians and regulators across trials in autosomal dominant polycystic kidney disease (ADPKD) limits shared decision-making. The Standardized Outcomes in Nephrology - Polycystic Kidney Disease
Yeoungjee Cho, A. Tong, J. Craig, R. Mustafa, A. Chapman, R. Perrone, C. Ahn, K. Fowler, V. Torres, R. Gansevoort, A. Ong, Helen Coolican, Juliana Tze-Wah Kao, T. Harris, Talia Gutman, Jenny I. Shen, A. Viecelli, David W. Johnson, E. Au, R. El-Damanawi, C. Logeman, A. Ju, Karine E. Manera, M. Chonchol, Dwight Odland, David A. Baron, Y. Pei, B. Sautenet, A. Rastogi, Ankit Sharma, G. Rangan   +30 more
semanticscholar   +1 more source

Emphysematous polycystic infection in a patient on peritoneal dialysis

Saudi Journal of Kidney Diseases and Transplantation, 2014
Emphysematous infection of the cysts in patients with polycystic kidney disease is very rare and seldom reported. We herein report a case of emphysematous polycystic infection in a 61-year-old male patient who was on peritoneal dialysis for end-stage ...
Shankar Prasad Nagaraju, Ankur Gupta, Brendan B Mccormick, Ashish Khandelwal   +3 more
doaj   +1 more source

Advances in Autosomal Dominant Polycystic Kidney Disease: A Clinical Review

Kidney Medicine, 2020
Polycystic kidney disease (PKD) is a multiorgan disorder resulting in fluid-filled cyst formation in the kidneys and other systems. The replacement of kidney parenchyma with an ever-increasing volume of cysts eventually leads to kidney failure. Recently,
Niloofar Nobakht, Ramy M. Hanna, Maha Al-Baghdadi, Khalid Mohammed Ameen, Farid Arman, Ehsan Nobahkt, Mohammad Kamgar, Anjay Rastogi   +7 more
doaj   +1 more source