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A pilot study of magnetic resonance fingerprinting and radiomics analysis in autosomal dominant polycystic kidney disease. [PDF]

Kidney Int
Kremer LE, Kretzler ME, MacAskill CJ, Smothers JB, Flask CA, Dell KM, Prasad PV, Giurcanu MC, Li F, Armato SG, Chapman AB.   +10 more
europepmc   +1 more source

Polycystic kidney disease [PDF]

Nature Reviews Disease Primers, 2018
Cystic kidneys are common causes of end-stage renal disease, both in children and in adults. Autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD) are cilia-related disorders and the two main forms of monogenic cystic kidney diseases.
Dorien Peters, Peter C Harris, Lisa M Guay-Woodford   +2 more
exaly   +9 more sources

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Kynurenines in polycystic kidney disease

Journal of Nephrology, 2022
Abstract Background Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder, characterized by kidney cyst formation. A major pathological feature of ADPKD is the development of interstitial inflammation.
Jost, Klawitter, Matthew J, Jackson, Peter H, Smith, Katharina, Hopp, Michel, Chonchol, Berenice Y, Gitomer, Melissa A, Cadnapaphornchai, Uwe, Christians, Jelena, Klawitter   +8 more
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Polycystic Kidney Disease

Comprehensive Physiology, 2017
ABSTRACT Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix remodeling. Hereditary polycystic kidney disease
Joseph, Ghata, Benjamin D, Cowley
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Cilia and polycystic kidney disease

Seminars in Cell & Developmental Biology, 2021
Polycystic kidney disease (PKD), comprising autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD), is characterized by incessant cyst formation in the kidney and liver. ADPKD and ARPKD represent the leading genetic causes of renal disease in adults and children, respectively.
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Polycystic Disease of the Kidneys

Annals of Internal Medicine, 1928
Excerpt Although polycystic degeneration of the kidneys cannot be looked upon a rare disease, it may be regarded as relatively uncommon.
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Polycystic Kidney Disease

New England Journal of Medicine, 2004
Polycystic kidney diseases are inherited renal disorders due mainly to mutations in genes that regulate the development and function of cells that line renal tubules. This review outlines the clinical importance of polycystic kidney diseases and discusses the cell biology and molecular mechanisms that cause the formation of hundreds of cystic lesions ...
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Reversing polycystic kidney disease

Nature Genetics, 2021
A new study shows that re-expressing PKD genes early in the course of the disease can fully reverse polycystic kidney disease in mice. These results reveal an unexpected ability of the kidney to regenerate following genetic rescue of polycystin function.
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Polycystic kidney disease in a cat

Journal of Small Animal Practice, 1977
ABSTRACTBilateral polycystic kidney disease was diagnosed in a 3‐year‐old female Persian cat. An elevation of blood urea nitrogen, serum creatinine levels, and serum phosphorus were the only abnormalities found with serial serum chemical and urine analyses. Intravenous urography showed radiolucent areas in both kidneys.
J W, Northington, M M, Juliana
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