Results 21 to 30 of about 451,989 (311)
Kidney: polycystic kidney disease [PDF]
WIREs Developmental Biology, 2014 Polycystic kidney disease (PKD) is a life‐threatening genetic disorder characterized by the presence of fluid‐filled cysts primarily in the kidneys. PKD can be inherited as autosomal recessive (ARPKD) or autosomal dominant (ADPKD) traits. Mutations in either the PKD1 or PKD2 genes, which encode polycystin 1 and polycystin 2, are the underlying cause of
Gregory B. Vanden Heuvel +2 more
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Femoral Neuropathy Secondary to Autosomal Dominant Polycystic Kidney Disease: A Case Report [PDF]
Annals of Rehabilitation Medicine, 2018 Compressive femoral neuropathy is a disabling condition accompanied by difficulty in hip flexion and knee extension. It may result from retroperitoneal hematoma or bleeding, or from complications associated with pelvic, hip surgery, and renal transplants.
Jeehyun Yoo +5 more
doaj +1 more source
Feline Polycystic Kidney Disease: An Update
Veterinary Sciences, 2021 Polycystic kidney disease (PKD) is a disease that affects felines and other mammals, such as humans. The common name is autosomal dominant polycystic kidney disease (ADPKD) and causes a progressive development of fluid-filled cysts in the kidney and ...
Lorie Schirrer +2 more
doaj +1 more source
Radiological Imaging Diagnosis of Adult Renal Cystic Diseases and Management
The Iraqi Journal of Medical Sciences, 2020 Background: Renal cysts are a heterogonous group of cystic renal diseases that present in approximately 40% of the patients undergoing imaging. Objective: To describe the role of the radiological imaging methods for the diagnosis of adult renal ...
Saleh Akares, Ahmed Bahomil
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Phase Separation in Kidney Diseases: Autosomal Dominant Polycystic Kidney Disease and Beyond
Kidney Diseases, 2023 Background: The formation of biomolecular condensates via phase separation has emerged as a fundamental principle underlying the spatiotemporal coordination of biological activities in cells.
Lirong Zhang +4 more
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Fetal polycystic kidney disease: Pathological overview
Journal of the Scientific Society, 2013 Polycystic kidney disease is a rare developmental anomaly inherited as autosomal dominant or autosomal recessive. It is characterized by cystic dilatation of the collecting ducts frequently associated with hepatic involvement and progression to renal ...
Sunita B Patil +3 more
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Exploring the Spectrum of Kidney Ciliopathies
Diagnostics, 2020 Ciliopathies are a group of multi-organ diseases caused by the disruption of the primary cilium. This event leads to a variety of kidney disorders, including nephronophthisis, renal cystic dysplasia, and renal cell carcinoma (RCC).
Matteo Santoni +7 more
doaj +1 more source
Gene therapy for pediatric genetic kidney diseases
Pediatric Discovery, 2023 Genetic kidney disease is the main cause of chronic kidney disease in children. While the pathogenic genes associated with most genetic kidney diseases have been identified, the underlying mechanisms of disease initiation remain ambiguous, and effective ...
Yi Lu +4 more
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Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease [PDF]
, 2016 The neurohypophysial hormone arginine vasopressin (AVP) acts by three distinct receptor subtypes: V1a, V1b, and V2. In the liver, AVP is involved in ureogenesis, glycogenolysis, neoglucogenesis and regeneration. No data exist about the presence of AVP in
Alpini, Gianfranco +11 more
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Genetic Complexity of Autosomal Dominant Polycystic Kidney and Liver Diseases.
Journal of the American Society of Nephrology, 2017 Data indicate significant phenotypic and genotypic overlap, plus a common pathogenesis, between two groups of inherited disorders, autosomal dominant polycystic kidney diseases (ADPKD), a significant cause of ESRD, and autosomal dominant polycystic liver
E. Cornec-Le Gall, V. Torres, P. Harris
semanticscholar +1 more source