Autosomal recessive polycystic kidney disease [PDF]
Nephrology Dialysis Transplantation, 1996 Autosomal recessive polycystic kidney disease (ARPKD) is a rare inherited disorder which usually becomes clinically manifest in early childhood. With increasing knowledge and improving diagnostic techniques it has become evident that the spectrum of ARPKD is much more variable than was previously thought.
K, Zerres +3 more
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Cystic Kidney Diseases From the Adult Nephrologist’s Point of View
Frontiers in Pediatrics, 2018 Cystic kidney diseases affect patients of all age groups with the onset spanning from prenatal disease to late adulthood. Autosomal-dominant polycystic kidney disease (ADPKD) is by far the most common renal cystic disease.
Roman-Ulrich Müller, Thomas Benzing
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Renal cell carcinoma in autosomal dominant polycystic kidney disease: A case report
Radiology Case Reports, 2023 Autosomal dominant polycystic kidney disease (ADPKD) is one of the congenital cystic renal diseases with the highest incidence. ADPKD was suspected of being a risk factor for the emergence of RCC.
Gullyawan Rooseno +3 more
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MicroRNAs and Polycystic Kidney Disease [PDF]
Drug Discovery Today: Disease Models, 2013 Polycystic kidney disease (PKD), the most common genetic cause of chronic renal failure, is characterized by the presence of numerous fluid-filled cysts in renal parenchyma. Despite recent progress, no FDA-approved therapy is available to retard cyst growth.
Lama, Noureddine +2 more
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Microvesicles and exosomes: new players in metabolic and cardiovascular disease [PDF]
, 2016 The past decade has witnessed an exponential increase in the number of publications referring to extracellular vesicles (EVs). For many years considered to be extracellular debris, EVs are now seen as novel mediators of endocrine signalling via cell-to ...
Charlotte Lawson +21 more
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Expert-level segmentation using deep learning for volumetry of polycystic kidney and liver [PDF]
Investigative and Clinical Urology, 2020 Purpose: Volumetry is used in polycystic kidney and liver diseases (PKLDs), including autosomal dominant polycystic kidney disease (ADPKD), to assess disease progression and drug efficiency.
Tae Young Shin +17 more
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Extracellular vesicles in kidneys and their clinical potential in renal diseases [PDF]
Kidney Research and Clinical Practice, 2021 Extracellular vesicles (EVs), such as exosomes and microvesicles, are cell-derived lipid bilayer membrane particles, which deliver information from host cells to recipient cells.
Sul A Lee, Chulhee Choi, Tae-Hyun Yoo
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Nonobstructing Colonic Dilatation and Colon Perforations Following Renal Transplantation [PDF]
, 1990 Nonobstructing colonic dilatation has not been commonly reported following renal transplantation, and colon perforations carry a high morbidity and mortality in this population.
Hakala, TR +5 more
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Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
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Histone Methyltransferases as Therapeutic Targets for Kidney Diseases
Frontiers in Pharmacology, 2019 Emerging evidence has demonstrated that epigenetic regulation plays a vital role in gene expression under normal and pathological conditions. Alterations in the expression and activation of histone methyltransferases (HMTs) have been reported in ...
Chao Yu +2 more
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