Results 111 to 120 of about 548,458 (391)

Pansomatostatin Agonist Pasireotide Long-Acting Release for Patients with Autosomal Dominant Polycystic Kidney or Liver Disease with Severe Liver Involvement: A Randomized Clinical Trial.

American Society of Nephrology. Clinical Journal, 2020
BACKGROUND AND OBJECTIVES We assessed safety and efficacy of another somatostatin receptor analog, pasireotide long-acting release, in severe polycystic liver disease and autosomal dominant polycystic kidney disease. Pasireotide long-acting release, with
M. Hogan, Julie A Chamberlin, Lisa E. Vaughan, Angela L Waits, Carly J Banks, Kathleen Leistikow, Troy Oftsie, Charles D. Madsen, Marie E. Edwards, J. Glockner, W. Kremers, P. Harris, N. LaRusso, V. Torres, T. Masyuk   +14 more
semanticscholar   +1 more source

Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery

Interdisciplinary Medicine, EarlyView.
We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia, Yang Luo   +14 more
wiley   +1 more source

A Diagnosis and Treatment of Liver Diseases: Integrating Batch Processing, Rule-Based Event Detection and Explainable Artificial Intelligence [PDF]

arXiv, 2023
Liver diseases pose a significant global health burden, impacting many individuals and having substantial economic and social consequences. Rising liver problems are considered a fatal disease in many countries, such as Egypt and Moldova. This study aims to develop a diagnosis and treatment model for liver disease using Basic Formal Ontology (BFO ...
arxiv  

Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. [PDF]

, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disease that leads to renal failure in the majority of patients. The very first pharmacological treatment, tolvaptan, received Food and Drug Administration approval in 2018 ...
Bourgeois, Bryan C, Kruger, Samantha L, Shillingford, Jonathan M, Torres, Jacob, Weimbs, Thomas   +4 more
core   +1 more source

The effect of atorvastatin on pancreatic beta cell requirement in women with polycystic ovary syndrome [PDF]

, 2017
Background There is an increased risk of developing T2DM in women with polycystic ovary syndrome (PCOS) and there is evidence that statins improve metabolic parameters in these patients.
Atkin, Stephen L., Coady, Anne Marie, Kilpatrick, Eric S., Sathyapalan, Thozhukat   +3 more
core   +2 more sources

Prevalence and predictors of nonalcoholic fatty liver disease in South Asian women with polycystic ovary syndrome

World Journal of Gastroenterology, 2020
BACKGROUND Polycystic ovary disease (PCOS) may be a risk factor for nonalcoholic fatty liver disease (NAFLD) due to common pathogenetic pathways, including insulin resistance and obesity. Both PCOS and NAFLD are more severe in South Asian women.
M. Shengir, S. Krishnamurthy, P. Ghali, M. Deschênes, P. Wong, Tianyan Chen, G. Sebastiani   +6 more
semanticscholar   +1 more source

Fuelling Recovery: Is There a Role for Radiation Therapists in Optimising Nutrition for Women With Breast Cancer?

Journal of Medical Radiation Sciences, EarlyView.
A study of 90 Australian women receiving breast cancer radiation therapy found none met dietary guidelines, with only 33% consuming enough fruit and 12% enough vegetables daily, indicating a crucial need for improvement in nutritional support during treatment.
Laura Feighan, Lesley MacDonald‐Wicks, Robin Callister, Yolanda Surjan   +3 more
wiley   +1 more source

Electrocardiogram-based diagnosis of liver diseases: an externally validated and explainable machine learning approach [PDF]

eClinicalMedicine 84 (2025) 103242
Background: Liver diseases present a significant global health challenge and often require costly, invasive diagnostics. Electrocardiography (ECG), a widely available and non-invasive tool, can enable the detection of liver disease by capturing cardiovascular-hepatic interactions. Methods: We trained tree-based machine learning models on ECG features
arxiv   +1 more source

Fully Automatic Liver Attenuation Estimation Combing CNN Segmentation and Morphological Operations [PDF]

, 2019
Manually tracing regions of interest (ROIs) within the liver is the de facto standard method for measuring liver attenuation on computed tomography (CT) in diagnosing nonalcoholic fatty liver disease (NAFLD). However, manual tracing is resource intensive.
arxiv   +1 more source

Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]

, 2019
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo, Ho, Bryan S, Kelley, Scott T, Sau, Lillian, Thackray, Varykina G   +4 more
core   +2 more sources