Results 211 to 220 of about 100,395 (290)

Prevalence of polycystic ovary syndrome and determinants of knowledge among women in the eastern province Saudi Arabia. [PDF]

Front Reprod Health
Al Shawan D, Alsaad M, Alhumaid B, Shabib F, Almulla S, AlThukair D, Alfawwaz H.   +6 more
europepmc   +1 more source

Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In a rat model of DHEA/DHT‐induced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxin‐interacting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng, Luxi Shangguan, Qi Shen, Zhengquan Zhu, Yaling Zhang, Jingwen Zhang, Guijun Yan, Shanmei Shen, Zou Xiang, Jianguo Ruan, Yanting Wen, Daojuan Wang, Yong Wang   +12 more
wiley   +1 more source

Cardiovascular Dysfunction in Polycystic Ovary Syndrome: Mitochondrial and Inflammatory Mechanisms. [PDF]

Biomed Res Int
Badejogbin OC, Agunloye MO, Chijioke-Agu OE, Olubiyi MV, Olugbuyiro SO, Soetan OA, Bamgbose OA, Olaleye TO.   +7 more
europepmc   +1 more source

Aptamer‐Functionalized Silicon Nanonet‐Based Field‐Effect‐Transistors Combined with Machine Learning for Real‐Time Detection of 17β‐Estradiol

Advanced Sensor Research, Volume 5, Issue 4, April 2026.
Schematic workflow of the BioFET (biological field‐effect transistor)based hormone sensing system, including (1) 17β‐estradiol (E2) sample preparation in PBS (phosphate‐buffered saline), (2) DNA aptamerfunctionalized BioFET sensing, (3) electrical signal acquisition (IV: currentvoltage characteristics), and (4) machine‐learning (ML)based data analysis.
Alexandra Parichenko, Anastasiia Gorelova, Wiana Butko, Chenchen Wang, Stephanie Klinghammer, Leif Riemenschneider, Bergoi Ibarlucea, Santiago Meliá, Shirong Huang, Gianaurelio Cuniberti   +9 more
wiley   +1 more source

Diagnosed Polycystic Ovary Syndrome and Associated Severe Maternal Morbidity.

Gynecol Obstet Invest
Hincapie MA, Ray JG, Shellenberger J, Velez MP.   +3 more
europepmc   +1 more source

sc-eQTL unveil immunogenetic architecture of polycystic ovary syndrome. [PDF]

Sci Rep
Xu X, Bao Y, Zhang Q, Wang L, Wang H.
europepmc   +1 more source

Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

Advanced Science, Volume 13, Issue 23, 23 April 2026.
This study reveals a pivotal epigenetic regulatory role for the histone acetyltransferase p300, demonstrating that its acetylation of histone 3 at lysine 18 and 27 (H3K18ac and H3K27ac), alongside the formation of the p300/BRD4/SP1 complex, drives AR activation and ovarian fibrosis in PCOS.
Zhengquan Zhu, Yihan Wang, Haiyun Chen, Xinye Yu, Tingyu Wang, Yajing Weng, Meihong Guo, Ying Huang, Gaojian Tao, Wangsen Cao, Yong Wang, Daojuan Wang   +11 more
wiley   +1 more source

Edible bird's nest ameliorates hyperandrogenism and gonadotropin imbalance in a rat model of polycystic ovary syndrome. [PDF]

Front Nutr
Jiao Y, Yuan M, Chen L, Qiu S, Chen J, Wang D.   +5 more
europepmc   +1 more source

Real‐Time and High‐Resolution NIR‐II‐L Imaging of Netrin‐1‐Mediated Neurovascular Coupling Driven by Dose‐Dependent Electroacupuncture

Advanced Science, Volume 13, Issue 19, 2 April 2026.
Disrupted neurovascular coupling contributes to ovarian dysfunction in polycystic ovary syndrome. Using near‑infrared II long‑wavelength imaging, this study visualizes how electroacupuncture dynamically regulates ovarian blood vessels in vivo. Immediate and cumulative stimulation elicit distinct vascular responses via a Netrin‐1 dependent mechanism ...
Yicong Wang, Zi‐Han Chen, Jiajia Li, Wei Hu, Ying Cao, Yu Wang, Xiaoyu Tong, Wenhan Lu, Yuze Yang, Yuehao Wang, Yan Xiao, Wenhao Gao, Yuning Chen, Yuyan Hou, Fan Zhang, Yi Feng   +15 more
wiley   +1 more source

Commentary: Clinical utility of anthropometric parameters in identifying glucose dysregulation in women with polycystic ovary syndrome. [PDF]

Front Endocrinol (Lausanne)
Liu J, Hu Z, Pan J.
europepmc   +1 more source