Results 221 to 230 of about 68,966 (291)

Efficacy of Weight‐Lowering Agents on Fat Distribution: A Systematic Review and Network Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity Reviews, Volume 27, Issue 7, July 2026.
ABSTRACT Background Pharmacotherapy offers a potential solution for individuals with overweight and obesity to decrease their body weight. However, there is limited knowledge of the effects of antiobesity agents on the distribution of body fat. Methods The PubMed, Embase, and Cochrane Library databases were reviewed for randomized controlled trials ...
Xiuqi Qiao   +4 more
wiley   +1 more source

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang   +15 more
wiley   +1 more source

Prevalence of polycystic ovary syndrome among adolescents depending on the adopted diagnostic criteria. [PDF]

open access: yesFront Endocrinol (Lausanne)
Jakubowska-Kowal K   +3 more
europepmc   +1 more source

Genetic Correlation and Causal Inference Between Female Fat Distribution and Preeclampsia: An Integrative Genomic Study

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
We conducted integrative genomic analyses of large‐scale GWAS summary data to explore the shared polygenic architecture and causal link between female fat distribution (WHRadjBMI) and preeclampsia, identifying novel loci and critical vascular–immune pathways with implications for risk prediction.
Man Wang   +5 more
wiley   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen   +13 more
wiley   +1 more source

Outcome-specific shifts in homocysteine-androgen correlations in polycystic ovary syndrome. [PDF]

open access: yesFront Endocrinol (Lausanne)
Han Q, Zhao J, Li M, Xin M, Yin X, He J.
europepmc   +1 more source

Social deprivation, race, and metabolic syndrome in patients with polycystic ovary syndrome. [PDF]

open access: yesJ Endocr Soc
Lee IT   +6 more
europepmc   +1 more source

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