Results 41 to 50 of about 98,529 (269)
Background and objective Polycystic ovary syndrome is one of the most common types of endocrine and metabolic diseases in women of reproductive age that needs to be screened early and assessed non-invasively.
Weiying Wang +8 more
doaj +1 more source
Polycystic ovaries and polycystic ovary syndrome
In the 50 years or so since the description by Irving F. Stein and Michael L. Leventhal of their finding of unexpectedly enlarged ovaries in a group of women with amenorrhea1, the syndrome we associate with their names has become widely recognized, variously interpreted and a subject of continual fascination for scores of reproductive scientists and ...
openaire +2 more sources
Polycystic Ovary Syndrome [PDF]
__Abstract__ The polycystic ovary syndrome (PCOS) was first described in 1935 by Stein and Leventhal as an association of amenorrhoea, obesity and a typical, polycystically enlarged, appearance of the ovaries at laparatomy1.
Valkenburg, O. (Olivier)
core +2 more sources
The impact of female obesity on the outcome of fertility treatment [PDF]
Peer reviewedPublisher ...
Abha Maheshwari +53 more
core +3 more sources
Leptin, polycystic ovaries and polycystic ovary syndrome [PDF]
As soon as leptin was discovered four years ago, its potential as a player in the polycystic ovary syndrome (PCOS) was explored in a primitive way, though little light was shed on the enigma that is PCOS. As a second wave of leptin research is now available, we review how the expanded role of the cytokine in reproduction might yet impact upon our ...
H S, Jacobs, G S, Conway
openaire +2 more sources
Nutritional Management in Polycystic Ovary Syndrome: Challenges and opportunities [PDF]
PCOS is one of the most common endocrine diseases affecting women of reproductive age. Its etiology remains unresolved but it is thought to have a genetic basis as well as interactions with other environmental factors.
Ghazeeri, G. +5 more
core +1 more source
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou +10 more
wiley +1 more source
Objective: Nonalcoholic fatty liver disease is the commonest diffuse liver disease, of which women with polycystic ovary syndrome are at an increased risk.
Na Di +8 more
doaj +1 more source
The experiences of women with polycystic ovary syndrome on a very low-calorie diet [PDF]
The research was funded by an educational grant from LighterLife. Broom was the Medical Director for LighterLife at the time of the research. Johnson is the Head of Nutrition and Research at LighterLife.
Broom, John +5 more
core +3 more sources
Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source

