Results 71 to 80 of about 149 (135)

Glucagon‐like peptide 1 (GLP‐1) receptor agonists' use during pregnancy: Safety data from regulatory clinical trials

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The prevalence of diabetes and obesity continues to rise in women of reproductive age, with significant implications for both mother and foetus. Glucagon‐like peptide‐1 receptor agonists are effective treatments of diabetes and obesity. However, no Glucagon‐like peptide‐1 receptor agonists are currently approved for use during pregnancy ...
Claire H. Parker, Craig Slattery, Donal J. Brennan, Carel W. le Roux   +3 more
wiley   +1 more source

Management of metabolic dysfunction–associated steatotic liver disease (MASLD)—An expert consensus statement from Indian diabetologists' perspective

Diabetes, Obesity and Metabolism, EarlyView.
Abstract In India, the increasing prevalence of diabetes and obesity poses a significant threat towards a surge in the incidence of metabolic dysfunction‐associated steatotic liver disease (MASLD), formerly known as non‐alcoholic fatty liver disease (NAFLD).
Abdul Hamid Zargar, Anil Bhansali, Anirban Majumdar, Anuj Maheshwari, Arpandev Bhattacharyya, Arundhati Dasgupta, Banshi Damodarlal Saboo, Bipin Kumar Sethi, Debmalya Sanyal, Krishna G. Seshadri, Neeta Rohit Deshpande, Nitin Kapoor, Om Jitendra Lakhani, Pradeep Gopal Talwalkar, Pramila Kalra, Rabindera Nath Mehrotra, Rakesh Kumar Sahay, Rishi Shukla, Saket Kant, Sambit Das, Sanjay Chunilal Agarwal, Sanjeev Ratnakar Phatak, Shanmugasundar G., Shashank Rameshchandra Joshi, Shehla Sajid Shaikh, Sosale Ramachandra Aravind, Soumik Goswami, Sujoy Ghosh, Vijay Kumar Panikar, Viswanathan Mohan   +29 more
wiley   +1 more source

Hidradenitis Suppurativa Treatment During Pregnancy and Lactation: Navigating Challenges

International Journal of Dermatology, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin condition primarily affecting skin folds such as the axilla, groins, and the inframammary, perineal, and perianal regions. It is characterized by painful abscesses, sinus tracts, and scarring.
Laşin Özbek, Mustafa Güldan, Erkan Alpsoy, Seçil Vural   +3 more
wiley   +1 more source

Young‐onset type 2 diabetes—Epidemiology, pathophysiology, and management

Journal of Diabetes Investigation, EarlyView.
The burden of young‐onset type 2 diabetes is increasing globally, disproportionately affecting non‐White ethnic groups and low‐ and middle‐income countries. Young‐onset type 2 is more heterogeneous regarding the genetic and environmental contributions to its underlying pathophysiology, which poses challenges for glycemic management.
Andrea O.Y. Luk, Hongjiang Wu, Yingnan Fan, Baoqi Fan, Chun Kwan O, Juliana C.N. Chan   +5 more
wiley   +1 more source

New insights on hidradenitis suppurativa phenotypes and treatment response: An exploratory automated analysis of the SUNSHINE and SUNRISE trials

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Hidradenitis suppurativa (HS) clusters in adults with moderate to severe HS in the SUNSHINE and SUNRISE phase 3 trials and responses to secukinumab treatment by cluster. Graphical abstract detailing three panels that describe (i) the population, study design and cluster analysis method used in this analysis; (ii) the baseline clustering analysis ...
Anna Passera, Elisa Muscianisi, David Demanse, Ginette A. Okoye, Gregor B. E. Jemec, Tiffany Mayo, Jennifer Hsiao, Vivian Y. Shi, Angel S. Byrd, Xiaoling Wei, Lorenz Uhlmann, Marc Vandemeulebroecke, Shoba Ravichandran, Martina L. Porter   +13 more
wiley   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 899-941, May 2025.
HS treatment algorithm. Abstract Introduction This second part of the S2k guidelines is an update of the 2015 S1 European guidelines. Objective These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS ...
C. C. Zouboulis, F. G. Bechara, F. Benhadou, V. Bettoli, Z. Bukvić Mokos, V. Del Marmol, M. Dolenc‐Voljč, E. J. Giamarellos‐Bourboulis, Ø. Grimstad, P. Guillem, B. Horváth, R. E. Hunger, J. R. Ingram, D. Ioannidis, E. Just, L. Kemény, B. Kirby, A. I. Liakou, B. M. McGrath, A. V. Marzano, Ł. Matusiak, A. Molina‐Leyva, A. Nassif, M. Podda, E. P. Prens, F. Prignano, H. Raynal, M. Romanelli, D. M. L. Saunte, A. Szegedi, J. C. Szepietowski, T. Tzellos, S. Valiukevičienė, H. H. van der Zee, K. R. van Straalen, B. Villumsen, G. B. E. Jemec   +36 more
wiley   +1 more source

Proactive Management of Lactation in the Birth Hospital to Ensure Long‐Term Milk Production and Sustainable Breastfeeding

Journal of Midwifery &Women's Health, Volume 70, Issue 2, Page 343-349, March/April 2025.
Abstract Individuals who are at risk of not achieving a full milk supply are often overlooked in scientific literature. There is available guidance to help establish an adequate milk supply for healthy individuals experiencing a physiologic labor and birth, and there are robust recommendations for the lactating parents of small, sick, and preterm ...
Diane L. Spatz, Salomé Álvarez Rodríguez, Sarah Benjilany, Barbara Finderle, Aleyd von Gartzen, Ann Yates, Jessica Brumley   +6 more
wiley   +1 more source

Effect of tirzepatide on weight and metabolism in a multiethnic cohort with and without diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 5, Page 2891-2895, May 2025.
Sara El Ghandour, Fatemeh Akbarpoor, Momina Malik, Madeeha Kalsekar, Sara Vidha, Prisha Bhatia, Nisrine Al Ghazal, Jeyaseelan Lakshmanan, Rabia Cherquaoui, Farah Al Abed, Mona Jomaa, Georges Hajje, Samuel B. Ho, Maryam Alsaeed   +13 more
wiley   +1 more source

Neuroactive steroid exposure impacts neurodevelopment: Comparison of human and rodent placental contribution

Journal of Neuroendocrinology, EarlyView.
Abstract The placenta is a fetal endocrine organ that secretes many neuroactive factors, including steroids, that play critical roles in brain development. The study of the placenta‐brain axis and the links between placental function and brain development represents an emerging research area dubbed “neuroplacentology.” The placenta drives many ...
Claire‐Marie Vacher, Alex Tsompanidis, Morgan R. Firestein, Anna A. Penn   +3 more
wiley   +1 more source

Neuroendocrine mechanisms responsible for elevated gonadotrophin‐releasing hormone and luteinising hormone pulses in polycystic ovary syndrome

Journal of Neuroendocrinology, EarlyView.
Abstract Polycystic ovary syndrome (PCOS) is the leading cause of anovulatory infertility in premenopausal individuals with ovaries worldwide. Despite the diagnostic features of anovulation, ovarian cysts, and hyperandrogenemia, which indicate that ovary dysfunction is the cause of the syndrome, changes in central neuroendocrine circuits are a ...
Aleisha M. Moore
wiley   +1 more source