Results 131 to 140 of about 67,068 (268)

Photodynamic priming (PDP) targets platinum resistance from chronic perfluoroalkyl substances (PFAS) exposure in ovarian cancer cells

Photochemistry and Photobiology, EarlyView.
PFAS are environmental contaminants that induce chemoresistance in ovarian cancer cells. This study evaluated BPD‐PDP or ALA‐PpIX‐PDP in combination with carboplatin or doxorubicin to overcome PFAS‐induced chemoresistance in two cell cohorts: (i) PFAS chronically‐exposed and (ii) PFAS outgrown cells (which underwent a “recovery period” after chronic ...
Brittany P. Rickard, Meghan M. Dillon, Lauren A. Sapienza‐Lundie, Suzanne E. Fenton, Imran Rizvi   +4 more
wiley   +1 more source

Epigenetic Perspectives on Maternal Gut Microbiota's Impact on Embryonic and Fetal Development

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
This review summarizes how maternal health and nutrition shape gut microbiota via epigenetics to regulate embryonic development. It highlights microbiota‐embryo interactions, disruption by prenatal chemical exposures, and personalized nutrition for disease prevention, offering novel insights and therapeutic targets.
Shoulong Xu, Yanjiao Huang, Chenyue Hu, Wenli Ding, Zhenwei Pu, Qiang Li, Zhiliang Xu   +6 more
wiley   +1 more source

Effects of inulin on intestinal flora and metabolism-related indicators in obese polycystic ovary syndrome patients

European Journal of Medical Research
Context Polycystic ovary syndrome (PCOS), a common endocrine disorder in women of reproductive age, is closely associated with chronic low-grade inflammation and metabolic disturbances.
Xiaorong Li, Bo Jiang, Ting Gao, Yan Nian, Xing Bai, Jiawen Zhong, Ling Qin, Zhengzheng Gao, Hao Wang, Xiaohong Ma   +9 more
doaj   +1 more source

The Risk of GLP‐1 Receptor Agonist (GLP‐1 RA) Exposure in Early Pregnancy. A Call to Action: Quantifying the Impact on Pregnancy Outcomes in the United Kingdom

Diabetes, Obesity and Metabolism, EarlyView.
Michael Stedman, Pensee Wu, Ian Halsall, Nadia Chaudhury, Barbara McGowan, Martin B. Whyte, Akheel Syed, Adrian Heald   +7 more
wiley   +1 more source

Kefir: A Potential Gut Microbiota Modulator: A Systematic Review of Human Interventional Studies

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Daily cow's milk kefir intake transiently enriches gut microbiota, modulates the intestinal environment by increasing SCFA and reducing pH and oxygen, and exerts antimicrobial effects via SCFAs, bacteriocins, exopolysaccharides, and microbial fractions, highlighting its potential for gut health promotion.
Mohammed Hamsho, Yazan Ranneh, Batoul Kaddour, Sundus Alfakhri, Hale Hacıbayram, Wijdan Shkorfu, Merve Terzi, Abdulmannan Fadel   +7 more
wiley   +1 more source

Effect of Glycyrrhizic Acid on Gonadotropins, Estradiol, Testosterone and Inflammatory Cytokines in Polycystic Ovarian Syndrome Rat Model

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017
Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders and most important cause of anovulation. High levels of inflammatory cytokines cause deterioration of polycystic ovary syndrome.
SD Sadoughi, Z Hassanzadeh
doaj  

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Translation and psychometric analysis of urdu version of modified polycystic ovary syndrome health related quality of life questionnaire (MPCOSQ-U)

BMC Women's Health
Background Polycystic ovary syndrome is a metabolic disorder prevalent among females of reproductive age. The symptoms of PCOS profoundly affect the quality of life of these females.
Rabbiya Zaman, Sarah Ehsan, Abeer Fatima, Sumaiyah Obaid, Javeria Shahzadi   +4 more
doaj   +1 more source

Implementing a Co‐Produced Women's Health Programme in an Integrated Care System

Public Health Challenges, Volume 5, Issue 2, June 2026.
A co‐produced women's health programme is implemented within an integrated care system using a structured, six‐phase service improvement approach. Engagement with over 1200 participants identifies barriers, priorities, and service gaps. Findings inform the co‐design of five targeted service models.
Susan Conquer, Lizzie Mapplebeck, Annetta Bradshaw, Lisa Nobes, Camille Cronin   +4 more
wiley   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source