Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS
In a rat model of DHEA/DHTâinduced PCOS and in granulosa cells (GCs), upregulated DNMT1, DNMT3A, and DNMT3B inhibit TXNIP degradation, leading to TXNIP accumulation, which drives ovarian fibrosis and tissue injury. ABSTRACT Hyperandrogenism and elevated thioredoxinâinteracting protein (TXNIP) are potential causes of infertility in women with polycystic
Yajing Weng +12 more
wiley +1 more source
Investigation of Dietary Habits, Anthropometric Profile, and Hormone Levels of Women of Childbearing Age With Polycystic Ovary Syndrome (PCOS). [PDF]
Ashraf A, Ashraf H.
europepmc +1 more source
Comparative Analysis of Heart Rate Variability in Women with and Without Polycystic Ovary Syndrome (PCOS). [PDF]
Sarathivarman S +6 more
europepmc +1 more source
An ovine model shows that subcutaneous adipose tissue fibrosis occurs early in polycystic ovary syndrome (PCOS). [PDF]
Wang Y +4 more
europepmc +1 more source
Effects of Ketogenic Diet (KD) on Metabolic, Endocrine, and Reproductive Outcomes in Overweight/Obese Women With Polycystic Ovary Syndrome (PCOS): A Systematic Review. [PDF]
Diha AM +7 more
europepmc +1 more source
Multimodal Integration of Genomic Data Reveals Regulatory Mechanisms at the Polycystic Ovary Syndrome (PCOS)-Associated 12q13.2 Locus. [PDF]
Harris RA, McAllister JM, Strauss JF.
europepmc +1 more source
Targeting Polycystic Ovary Syndrome (PCOS) Pathophysiology with Flavonoids: From Adipokine-Cytokine Crosstalk to Insulin Resistance and Reproductive Dysfunctions. [PDF]
Dutta S +6 more
europepmc +1 more source
Impact of Hypocaloric Dietary Intervention on Phenotypic Presentations of Polycystic Ovary Syndrome (PCOS). [PDF]
Carter FE +5 more
europepmc +1 more source
The Mediating Effect of Body Appreciation on the Association Between Undiagnosed Polycystic Ovary Syndrome (PCOS) and Eating Disorders: A Cross-Sectional Study Among Lebanese Women. [PDF]
El Achkar N +8 more
europepmc +1 more source
Polycystic Ovary Syndrome (PCOS)-Specific Risk Appraisal of the Sunscreen Ultraviolet (UV) Filters (Oxybenzone/Octinoxate). [PDF]
Dutta S +5 more
europepmc +1 more source

