Results 51 to 60 of about 67,068 (268)

DIAGNOSIS OF PCOS IN WOMEN OF EARLY REPRODUCTIVE AGE USING THE DEVELOPED COMPUTER PROGRAM

open access: yesМать и дитя в Кузбассе, 2023
The purpose of the study – to develop a computer program for the diagnosis of polycystic ovary syndrome in women of early reproductive age. Material and methods. The object of the study was 400 women from 18 to 35 years old.
Светлана Ивановна Елгина   +1 more
doaj  

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao   +13 more
wiley   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

open access: yesAdvanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li   +15 more
wiley   +1 more source

GHRELIN AND INSULIN RESISTANCE IN A SAMPLE OF IRAQI WOMEN WITH POLYCYSTIC OVARY SYNDROME

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background: Polycystic ovary syndrome is associated with adiposity and metabolic changes predisposing to insulin resistance and diabetes mellitus. Ghrelin is an appetite-stimulating hormone, which acts through its receptor on the hypothalamus to regulate
Amal A. Hussein   +2 more
doaj   +4 more sources

Polycystic Ovary Syndrome (PCOS) and Infertility

open access: yesInternational Journal of Current Research and Review, 2021
Introduction: Polycystic ovary syndrome (PCOS) is characterized by a variety of reproductive and metabolic symptoms that affects 4–18% of reproductive-age women, depending on the diagnostic criteria used. PCOS is characterized by hormonal deregulation, insulin resistance, and metabolic disorders, all of which raise the risk of infertility, type ...
Hitashi Shawani, Shruti Singh
openaire   +1 more source

Inositols in Insulin Signaling and Glucose Metabolism [PDF]

open access: yes, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

open access: yesAdvanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi   +13 more
wiley   +1 more source

Individual 17-Hydroxyprogesterone Responses to hCG Are Not Correlated With Follicle Size in Polycystic Ovary Syndrome. [PDF]

open access: yes, 2019
Context:In women with polycystic ovary syndrome (PCOS), 17-hydroxyprogesterone (17-OHP) responses to gonadotropin stimulation vary from increased to indistinguishable compared with normal controls.
Chang, R Jeffrey   +5 more
core   +1 more source

Sexual and relational satisfaction in couples where the woman has polycystic ovary syndrome: a dyadic analysis [PDF]

open access: yes, 2014
STUDY QUESTION: How are objective characteristics of polycystic ovary syndrome (PCOS) and PCOS-related concerns associated with the sexual and relational satisfaction of PCOS women and their partners? SUMMARY ANSWER: Both objective PCOS characteristics (
Buysse, Ann   +5 more
core   +2 more sources

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