Results 121 to 130 of about 62,795 (319)

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia, Gioia, Stefania, Nicoletti, Valeria, PENTASSUGLIO, ILARIA, RIGGIO, Oliviero, VALENTE, MICHELE   +5 more
core   +1 more source

Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial

Haematologica, 2016
RESPONSE is an open-label phase 3 study evaluating the Janus kinase 1/Janus kinase 2 inhibitor ruxolitinib versus best available therapy for efficacy/safety in hydroxyurea-resistant or intolerant patients with polycythemia vera.
S. Verstovsek, A. Vannucchi, M. Griesshammer, T. Masszi, S. Durrant, F. Passamonti, C. Harrison, F. Pane, P. Zachée, K. Kirito, C. Besses, M. Hino, B. Moiraghi, Carole B. Miller, M. Cazzola, V. Rosti, I. Blau, R. Mesa, Mark M. Jones, H. Zhen, Jingjin Li, Nathalie Francillard, D. Habr, J. Kiladjian   +23 more
semanticscholar   +1 more source

Evaluation of blood erythroid parameters in male broiler chickens (Ross 308) with the Sysmex XT‐2000iV and Sysmex XN‐1000V analyzers and determination of hematological reference intervals obtained with manual and instrumental methods

Veterinary Clinical Pathology, EarlyView.
Abstract Background The presence of both nucleated RBC and thrombocytes in birds makes the determination of hematological variables difficult. This leads to time‐consuming manual evaluation. New‐generation analyzers are hypothesized to be both time‐saving and accurate. Objectives The objective was to evaluate the performance of two hematology analyzers
Damien Legroux, Laura Kersten, Gaelle Barral, Alexane Mauras, Thierry Buronfosse, Eve Ramery   +5 more
wiley   +1 more source

Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia [PDF]

, 2014
Regulation of erythropoiesis is achieved by integration of distinct signals. Among these, macrophages are emerging as erythropoietin-complementary regulators of erythroid development, particularly under stress conditions. We investigated the contribution
Abdel-Wahab, Omar, Breda, Laura, Casu, Carla, Crielaard, Bart J., Ebert, Benjamin L., Gardenghi, Sara, Ghaffari, Saghi, Giardina, Patricia J., Grady, Robert W., Gupta, Ritama, Guy, Ella, Levine, Ross L., Marongiu, Maria Franca, Ramos, Pedro, Rivella, Stefano, Van Rooijen, Nico   +15 more
core   +1 more source

Pannexin 1 and pannexin 3 differentially regulate the cancer cell properties of cutaneous squamous cell carcinoma

The Journal of Physiology, EarlyView.
Abstract figure legend PANX1 and PANX3 show opposite expression patterns in patient‐derived normal skin and cutaneous squamous cell carcinoma (cSCC) tumours, with PANX1 increased and PANX3 mRNA decreased in cSCC tumours compared to skin. Within the tumour PANX1 localizes to all regions, including tumour nests which house cSCC cancer cells and tumour ...
Brooke L. O'Donnell, Danielle Johnston, Ayushi Bhatt, Zahra Kardan, Dan Stefan, Andrew Bysice, Samar Sayedyahossein, Lina Dagnino, Matthew Cecchini, Sampath Kumar Loganathan, Kathryn Roth, Silvia Penuela   +11 more
wiley   +1 more source

Association between hemoglobin concentration and hypertension risk in native Tibetans at high altitude

The Journal of Clinical Hypertension
Previous studies examining the association between hemoglobin concentration and hypertension have yielded inconsistent results. There is still a lack of evidence regarding the association between hemoglobin concentration and hypertension risk in native ...
Xueting Liu, Changqiang Yang, Xin Zhang, Runyu Ye, Xinran Li, Zhipeng Zhang, Shanshan Jia, Lirong Sun, Qingtao Meng, Xiaoping Chen   +9 more
doaj   +1 more source

Male, Female, Other: Transgender and the Impact in Primary Care [PDF]

, 2016
Transgender includes patients at various stages of their journey. It is important that providers care for transgender patients with a culturally sensitive approach, awareness, and competent skill. There are new terms to learn.
Markwick, Laura
core   +2 more sources

Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera.

Blood, 2016
In β-thalassemia and polycythemia vera (PV), disordered erythropoiesis triggers severe pathophysiological manifestations. β-Thalassemia is characterized by ineffective erythropoiesis, reduced production of erythrocytes, anemia, and iron overload and PV ...
C. Casu, Paraskevi Rea Oikonomidou, Huiyong Chen, V. Nandi, Y. Ginzburg, Princy Prasad, R. Fleming, Y. Shah, E. Valore, E. Nemeth, T. Ganz, B. Macdonald, S. Rivella   +12 more
semanticscholar   +1 more source

Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia

Haematologica, 2013
Subclones homozygous for JAK2V617F are more common and larger in patients with polycythemia vera compared to essential thrombocythemia, but their role in determining phenotype remains unclear.
Anna L. Godfrey, Edwin Chen, Francesca Pagano, Yvonne Silber, Peter J. Campbell, Anthony R. Green   +5 more
doaj   +1 more source

Novel mutations in the von Hippel–Lindau gene associated with congenital polycythemia [PDF]

, 2015
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111073/1/pbc25407 ...
Bhambhani, Kanta, Callaghan, Michael U., Sidhu, Alpa   +2 more
core   +1 more source