Results 91 to 100 of about 28,321 (229)
Molecular mechanisms in haematological malignancies [PDF]
Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto +2 more
core
Cigarette smoking induces relative and absolute erythrocytosis (smokers' polycythemia). In patients with smokers' polycythemia complicated by chronic obstructive pulmonary disease, the incidence and mortality rate of pulmonary embolism increase ...
Kazuhide Iizuka +17 more
doaj +1 more source
Implementation of the JAK2V617F mutation analysis in the pathway of suspected myeloproliferative neoplasms in Groote Schuur Hospital [PDF]
We studied the implementation of JAK2 mutation analysis in conjunction with the World Health Organisation (WHO) guidelines in the pathway to MPN diagnosis in 279 patients presenting with one of three clinical scenarios: erythrocytosis, OR leukocytosis ...
Poulet, Erma
core
Development of a highly sensitive method for detection of JAK2V617F [PDF]
Background Ph- myeloproliferative neoplasms (MPNs) represent a heterogeneous group of chronic diseases characterized by increased expansion of hematopoietic cells of the myeloid lineage.
Anna H Zhao, Rufei Gao, Zhizhuang J Zhao
core +1 more source
The purpose of this study was to identify the incidence, causes and impact of non-adherence to oral and subcutaneous chronic treatments for patients with polycythemia vera or essential thrombocythemia.
Ronan Le Calloch +13 more
doaj +1 more source
GAMBARAN GEN JAK2 PADA PENDERITA POLISITEMIA VERA DI LABORATORIUM CEBIOR [PDF]
Background: Polycythemia vera ( PV ) is one of the myeloproliferative malignancies. The Jak2V617F mutation is found in approximately 96 percent of people with PV. JAK2 gene mutation results in the production of an activated JAK2 protein, which appears to
Faradz, Sultana MH +2 more
core +1 more source
STAT1 activation in association with JAK2 exon 12 mutations [PDF]
La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder ...
Godfrey, A.L. +33 more
core +4 more sources
A rare case of extramedullary hematopoiesis: when the pericardium produces blood cells
Background Cardiac tamponade is an extreme cardiological emergency, fatal in the absence of rapid intervention. This case report highlights a noteworthy and rare correlation between post-polycythemia vera myelofibrosis and extramedullary hematopoiesis ...
SALAH-EDDINE HAYAR +9 more
doaj +1 more source
One Grammar, Many Labels: Revisiting the Continuum of Myeloid Neoplasms
Hematological Oncology, Volume 44, Issue 3, May 2026.
Francesco Tarantini +18 more
wiley +1 more source
Chronic myelomonocytic leukemia as a transformation from polycythemia vera
The hallmark of Polycythemia vera (PV) is the presence of JAK2V617F mutation and increased RBC mass. Chronic myelomonocytic leukemia (CMML) is defined as persistent blood absolute monocyte count (AMC) >/= 1 × 109/L for at least 3 months with myeloid cell
Mirela Andrei +3 more
doaj +1 more source

