Results 71 to 80 of about 28,321 (229)
Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera
Case Reports in Neurology, 2011 Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa +3 more
doaj +1 more source
Cancer, Volume 132, Issue 10, 15 May 2026.Momelotinib demonstrated robust real‐world activity after ruxolitinib failure, with clinically meaningful improvements in spleen (≥50% spleen length reduction, 30.0%), symptoms (≥50% total symptoms score reduction, 39.2%), and anemia (major response, 35.7%) at 6 months.
Francesca Palandri +41 more
wiley +1 more source
Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis
Haematologica, 2019 Here we critically evaluate the role of elevated hematocrit as the principal determinant of thrombotic risk in polycythemia and erythrocytosis, defined by an expansion of red cell mass.
Victor R. Gordeuk +2 more
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HemaSphere, Volume 10, Issue 5, May 2026.Abstract Myeloproliferative neoplasms (MPNs) are clonal disorders of hematopoietic stem cells (HSCs) that are most frequently caused by acquired somatic mutations in JAK2. A number of conditional mouse models of JAK2‐V617F‐driven MPN have been generated that rely on Cre‐LoxP‐mediated activation, resulting in polyclonal disease.
Quentin Kimmerlin +9 more
wiley +1 more source
Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera
Haematologica, 2017 Up to 20% of patients with polycythemia vera have karyotypic abnormalities at the time of the initial diagnosis. However, the cytogenetic abnormalities in polycythemia vera have not been well characterized and their prognostic impact is largely unknown ...
Guilin Tang +13 more
doaj +1 more source
HemaSphere, Volume 10, Issue 5, May 2026.Abstract Interferon‐α (IFNα) remains a potent therapeutic option for myeloproliferative neoplasms (MPNs) with an activated JAK/STAT signaling axis. However, variable patient responses highlight the need for optimized combination strategies. Recent studies suggest a link between cyclin‐dependent kinase 6 (CDK6) and IFN signaling.
Brian Ringhofer +18 more
wiley +1 more source
Polycythemia Vera: New Diagnostic Concept and Its Types
Клиническая онкогематология, 2016 Polycythemia vera (PV) is a clonal Ph-negative myeloproliferative disorder characterized by excessive myeloid proliferation of three hematopoietic cell lineages leading to ineffective myelopoiesis.
Alla Mikhailovna Kovrigina, V. V. Baikov
doaj +1 more source
Nosocomial Co-Transmission of Avian Influenza A(H7N9) and A(H1N1)pdm09 Viruses between 2 Patients with Hematologic Disorders [PDF]
, 2016 A nosocomial cluster induced by co-infections with avian influenza A(H7N9) and A(H1N1)pdm09 (pH1N1) viruses occurred in 2 patients at a hospital in Zhejiang Province, China, in January 2014.
Bi, Y +21 more
core +1 more source
Thrombosis in Low‐Risk Polycythemia Vera: Insights From a Large Real‐World Cohort
Hematological Oncology, Volume 44, Issue 3, May 2026.ABSTRACT Polycythemia vera (PV) is a myeloproliferative neoplasm driven by JAK2 mutations and associated with thrombotic complications. Current risk stratification classifies younger patients without prior thrombosis as low‐risk (LR), yet long‐term outcomes in this group remain poorly defined.
Inbar Cohen +3 more
wiley +1 more source