Two-hit model of leukemogenesis in the evolution of polycythemia vera to acute myeloid leukemia [PDF]
Polycythemia vera (PV) is a chronic myeloproliferative disorder that can evolve to marrow fibrosis or acute leukemia (AML). Cytogenetic alterations can be detected in around 25% of patients at diagnosis and in up to 50% of those with progression.
Chauffaille, Maria de Lourdes Lopes Ferrari +2 more
core +1 more source
What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog
Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson +5 more
wiley +1 more source
Policitemia Vera en el perro : a propósito de un caso clínico [PDF]
Se describe un caso de policitemia vera en perro. Se discute el diagnóstico diferencial del proceso, pronóstico y tramiento.A c1inical case of primary polycythemia in a dog is described.
Aceña Fabián, M. Carmen +4 more
core
Studies on the iron metabolism of erythroblasts in various blood diseases [PDF]
The serum iron contents and the number of sideroblasts from various patients and the radioactivity of erythroblasts from the same patients incubated with Fe55 have been observed.
Kimura, Ikuro +2 more
core +1 more source
Polycythemia vera is a Philadelphia chromosome-negative myeloproliferative neoplasm. Chronic lymphocytic leukemia is a monoclonal expansion of a CD5+ CD19+ B lymphocytes.
Serdal Korkmaz +4 more
doaj +1 more source
Koljusisesed verevalumid tõelise polütsüteemiaga haigel kerge trauma järel [PDF]
Tõelise polütsüteemia diagnoosiga 54aastasel naishaigel kujunesid pärast kerget traumat – omalt jalalt kukkumist – ajusisene ja subduraalne verevalum vasemas ajupoolkeras.
Hein, Marju +3 more
core +2 more sources
Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia +5 more
core +1 more source
Detection of JAK2 exon 12 mutations in 15 patients with JAK2V617F negative polycythemia vera
To further characterize JAK2 exon 12 mutations, we performed molecular screening in 409 patients with polycythemia vera or unclear erythrocytosis with unmutated JAK2V617. The frequency of JAK2exon12 mutations was 10/63 (15.9%) in PV but only 5/346 (1.4%)
Susanne Schnittger +14 more
doaj +1 more source
Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage. [PDF]
Somatic mutations in the endoplasmic reticulum chaperone calreticulin (CALR) are detected in approximately 40% of patients with essential thrombocythemia (ET) and primary myelofibrosis (PMF).
Aungier, Juliet +17 more
core +1 more source
Superior Vena Cava Syndrome in a Patient with Polycytemia Vera: Diagnosis and Treatment
Polycythemia vera is a myeloproliferative disorder characterized by thrombotic complications both in the arterial and venous systems. We report the case of a 55-year-old patient affected by polycythemia vera, presenting with acute superior vena cava ...
Salvatore Lentini +3 more
doaj +1 more source

