Results 31 to 40 of about 300,077 (226)

Hereditary hemochromatosis and JAK2‐positive polycythemia vera

Clinical Case Reports, 2021
A 59‐year‐old man was diagnosed with JAK2‐positive polycythemia vera. Subsequently, further laboratory testing revealed elevated ferritin and iron saturation.
Ahmed Radwan, Ibraheem Othman
doaj   +1 more source

Double Thrombosis- Interesting Case of Polycythemia Vera [PDF]

Journal of Clinical and Diagnostic Research, 2020
Polycythemia vera is a myeloproliferative disorder which has a varied manifestation, one of it being venous thrombosis and arterial thrombosis which significantly contributes to the mortality and morbidity.
Subashini Subramanian, Siva Ranganathan Green   +1 more
doaj   +1 more source

The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera

Haematologica, 2009
Background The JAK2V617F mutation has been associated with constitutive and enhanced activation of neutrophils, while no information is available concerning other leukocyte subtypes.Design and Methods We evaluated correlations between JAK2V617F mutation ...
Lisa Pieri, Costanza Bogani, Paola Guglielmelli, Maria Zingariello, Rosa Alba Rana, Niccolò Bartalucci, Alberto Bosi, Alessandro M. Vannucchi   +7 more
doaj   +1 more source

Ruxolitinib for the prevention of thrombosis in polycythemia vera: a systematic review and meta-analysis.

Blood Advances, 2020
Ruxolitinib is a recommended second-line treatment for the prevention of thrombosis in patients with polycythemia vera who become resistant or intolerant to hydroxyurea; however, evidence regarding its efficacy in terms of thrombosis reduction is ...
A. Masciulli, A. Ferrari, A. Carobbio, A. Ghirardi, T. Barbui   +4 more
semanticscholar   +1 more source

Aquagenic Pruritus in Polycythemia Vera: Clinical Characteristics

Acta Dermato-Venereologica, 2018
Aquagenic pruritus is one of the main clinical features of polycythemia vera. The aim of this study was to analyse the clinical characteristics of aquagenic pruritus.
Edyta Lelonek, Łukasz Matusiak, Tomasz Wróbel, Jacek C. Szepietowski   +3 more
doaj   +1 more source

Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report

Journal of Medical Case Reports, 2018
Background Polycythemia vera is a myeloproliferative disease that sometimes evolves to myelofibrosis, causing splenomegaly and neutropenia. In this case report, we describe a patient with polycythemia vera and unexplained neutropenia who later turned out
Andreas Hanssønn Habberstad, Hoa Thi Tuyet Tran, Ulla Randen, Signe Spetalen, Ingunn Dybedal, Geir E. Tjønnfjord, Anders Erik Astrup Dahm   +6 more
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Concurrent Polycythemia Vera with Newly Diagnosed Multiple Myeloma: Case Report and Literature Review

Journal of Inflammation Research, 2023
Jing Yuan, Xuan Liu, Zhenzhen Wang, Liyuan Li, Fuxu Wang Department of Hematology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of ChinaCorrespondence: Fuxu Wang, Department of Hematology, The Second ...
Yuan J, Liu X, Wang Z, Li L, Wang F
doaj  

Persistent leukocytosis in polycythemia vera is associated with disease evolution but not thrombosis.

Blood, 2020
There are unresolved questions regarding the association between persistent leukocytosis and risk of thrombosis and disease evolution in polycythemia vera (PV), as much of the published literature on the topic does not appropriately utilize repeated ...
L. Ronner, N. Podoltsev, J. Gotlib, M. Heaney, A. Kuykendall, C. O'Connell, J. Shammo, Angela G. Fleischman, R. Scherber, R. Mesa, A. Yacoub, C. Perkins, S. Meckstroth, Lindsey Behlman, M. Chiaramonte, M. Salehi, Kimia Ziadkhanpour, Hellen Nguyen, Olivia Siwoski, A. Hung, M. Janania Martinez, Jenny Nguyen, Sagar V. Patel, R. Kollipara, Ami Dave, M. Randall, Mike Grant, M. Harrison, Paola Fernandez Soto, D. Tremblay, R. Hoffman, E. Moshier, J. Mascarenhas   +32 more
semanticscholar   +1 more source

New Perspectives on Polycythemia Vera: From Diagnosis to Therapy

International Journal of Molecular Sciences, 2020
Polycythemia vera (PV) is mainly characterized by elevated blood cell counts, thrombotic as well as hemorrhagic predisposition, a variety of symptoms, and cumulative risks of fibrotic progression and/or leukemic evolution over time.
A. Iurlo, D. Cattaneo, C. Bucelli, L. Baldini   +3 more
semanticscholar   +1 more source

Decrease in JAK2V617F allele burden is not a prerequisite to clinical response in patients with polycythemia vera

Haematologica, 2012
Background Although reduction in the JAK2V617F allele burden (%V617F) has been suggested as a criterion for defining disease response to cytoreductive therapy in polycythemia vera, its value as a response monitor is unclear.
Emil Kuriakose, Katherine Vandris, Y. Lynn Wang, William Chow, Amy V. Jones, Paul Christos, Nicholas C.P. Cross, Richard T. Silver   +7 more
doaj   +1 more source