Results 31 to 40 of about 412,436 (221)
Background Although reduction in the JAK2V617F allele burden (%V617F) has been suggested as a criterion for defining disease response to cytoreductive therapy in polycythemia vera, its value as a response monitor is unclear.
Emil Kuriakose +7 more
doaj +1 more source
BACKGROUND: The detection of molecular and cytogenetic alterations is important for the diagnosis, prognosis and classification of myeloproliferative neoplasms. OBJECTIVE: The aim of this study was to detect the following mutations: JAK2 V617F, JAK2 exon
Leonardo Caires dos Santos +5 more
doaj +1 more source
Review on Polycythemia vera (PV), with data on clinics, and the genes ...
Cavazzini, F +3 more
core +1 more source
A 70‐year‐old man with recurrent cerebral infarctions, a subdural hematoma, and atherosclerotic disease involving multiple extracranial vascular territories was subsequently diagnosed with polycythemia vera (PV). In patients with recurrent cerebrovascular events accompanied by otherwise unexplained persistent erythrocytosis, JAK2 mutation testing and ...
Hui Zhao +5 more
wiley +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Polycythemia vera as a presentation of renal angiomyolipoma: a case report
Introduction Angiomyolipoma is a common benign renal tumor composed of thick-walled blood vessels, smooth muscle, and adipose tissue. It may be found incidentally during workup for suspected renal disease.
Lin Ming-Shyan +7 more
doaj +1 more source
JAK2 Variant and Parkinsonian Syndromes: Coincidence or Pathophysiological Link?
Abstract Background JAK2 variants are a hallmark of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythemia. These disorders are often associated with thrombotic and inflammatory complications. From a movement disorder perspective, chorea is a rare but well‐recognized neurological occurrence in this context ...
Elena Ardila Jurado +5 more
wiley +1 more source
ABSTRACT Purpose The feasibility and reproducibility of adapting the T2‐Relaxation‐Under‐Spin‐Tagging (TRUST) MRI sequence for noninvasive measurement of venous oxygenation in the upper arm were investigated, aiming to enable future in vivo validation of T2b‐oxygenation calibration curves in sickle cell disease (SCD).
J. Diogo Fernandes +5 more
wiley +1 more source
We report the final 2-year end-of-study results from the first clinical trial investigating combination treatment with ruxolitinib and low-dose pegylated interferon-α2 (PEG-IFNα2).
Anders Lindholm Sørensen +19 more
doaj +1 more source
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo +3 more
wiley +1 more source

