Results 11 to 20 of about 412,436 (221)

Aquagenic Pruritus in Polycythemia Vera: Clinical Characteristics

open access: yesActa Dermato-Venereologica, 2018
Aquagenic pruritus is one of the main clinical features of polycythemia vera. The aim of this study was to analyse the clinical characteristics of aquagenic pruritus.
Edyta Lelonek   +3 more
doaj   +2 more sources

Polycythemia vera masked due to severe iron deficiency anemia [PDF]

open access: yesHematology/Oncology and Stem Cell Therapy, 2018
Polycythemia vera is one of the chronic myeloproliferative diseases and very few patients present with its actual clinical manifestations. The most common findings are increased red cell mass and an increased leukocyte count with decreased erythropoietin.
Shweta Kambali, Asma Taj
doaj   +3 more sources

Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera

open access: yesCase Reports in Neurology, 2011
Spinal arterial vascularization is supplied by a large anastomotic net, making spinal ischemic events far less common than ischemic cerebral strokes. Polycythemia vera, due to blood hyperviscosity and activated platelet aggregation, is associated with a ...
Sónia Costa   +3 more
doaj   +2 more sources

Papel de la activación leucocitaria y plaquetaria en la trombosis de los síndromes mieloproliferativos crónicos [PDF]

open access: yes, 2008
[spa] INTRODUCCIÓN Y OBJETIVOS: La causa fundamental de la trombosis en la policitemia vera y la trombocitemia esencial es el aumento de la viscosidad sanguínea secundaria a la eritrocitosis así como el incremento del número de plaquetas y las ...
Álvarez Larrán, Alberto
core   +6 more sources

Muramidase in Polycythemia Vera [PDF]

open access: yesBlood, 1970
Abstract The serum muramidase levels of 45 patients with polycythemia vera were found to be significantly elevated above the values in 20 normal subjects. The patients with polycythemia vera who were studied included those with active disease, those controlled with myelosuppressive agents and those in the spent phase.
R A, Binder, H S, Gilbert
openaire   +2 more sources

Studies of JAK2 mutations in myeloproliferative disorders [PDF]

open access: yes, 2008
Myeloproliferative disorders (MPD) are diseases characterized by clonal hematopoiesis with overprodution of mature cells from erythroid, megakaryocytic and myeloid lineages.
Li, Sai
core   +1 more source

Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy

open access: yesHaematologica, 2008
We analyzed the effect of hydroxyurea on the JAK2V617F allelic ratio (%JAK2V617F), measured in purified blood granulocytes, of patients with polycythemia vera and essential thrombocythemia.
François Girodon   +8 more
doaj   +1 more source

Clonal analyses reveal associations of JAK2V617F homozygosity with hematologic features, age and gender in polycythemia vera and essential thrombocythemia

open access: yesHaematologica, 2013
Subclones homozygous for JAK2V617F are more common and larger in patients with polycythemia vera compared to essential thrombocythemia, but their role in determining phenotype remains unclear.
Anna L. Godfrey   +5 more
doaj   +1 more source

The haematocrit and platelet target in polycythemia vera [PDF]

open access: yes, 2007
Polycythemia vera (PV) is a chronic myeloproliferative disorder whose major morbidity and mortality are thrombohaemorragic events and progression to acute leukaemia or myelofibrosis.
Di Nisio M   +14 more
core   +1 more source

PREFERENTIAL NUCLEAR ACCUMULATION OF JAK2V617F IN CD34+ BUT NOT IN GRANULOCYTIC, MEGAKARYOCYTIC OR ERYTHROID CELLS OF PATIENTS WITH PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE NEOPLASIA. [PDF]

open access: yes, 2010
Recently, Dawson et al. identified a previously unrecognized nuclear role for JAK2 in the phosphorylation of the tyrosine 41 of the histone H3 with the exclusion of HP1a from chromatin and resulting in a disregulation of several JAK2-regulated genes such
Rinaldi, Ciro Roberto
core   +2 more sources

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