Results 61 to 70 of about 1,486 (206)

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, Volume 4, Issue 3, May 2026.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Nucleic Acid-Based Therapeutics for Periodontal Tissue Regeneration: A Comprehensive Review

Applied Sciences
Polydeoxyribonucleotides (PDRNs) and polynucleotides (PNs) are biologically active DNA-derived polymers with emerging applications in regenerative dentistry. Acting through adenosine A2A receptor activation and modulation of inflammatory responses, these
Jwa-Young Kim, Min-Ho Hong, Seong-Gon Kim, Umberto Garagiola   +3 more
doaj   +1 more source

Real‐World Use of Polynucleotide Injections in Scar Prevention and Management: A Nationwide Survey of Korean Society for Anti‐Aging Dermatology (KAAD) Dermatologists

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Scarring is a common dermatologic concern with both aesthetic and functional implications. Polynucleotide (PN)‐based injectables have emerged as medical devices in dermatologic practice; however, real‐world evidence on their use in scar management remains limited.
Nark Kyoung Rho, Kwang Ho Han, Boncheol Leo Goo, Hei Sung Kim   +3 more
wiley   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, Volume 15, Issue 13, 3 April 2026.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Combination Therapy of Polydeoxyribonucleotide and Microcurrent in Muscle Regeneration on Cast‐Induced Muscle Atrophy in Rabbit [PDF]

, 2022
Dong Rak Kwon, Yong Suk Moon, Do Yun Kwon   +2 more
openalex   +1 more source

Advanced Regenerative Drainage and Immunomodulatory Protocol for Dermal Filler–Induced Skin Necrosis: A Prospective Clinical Case Series

Journal of Cosmetic Dermatology, Volume 25, Issue 4, April 2026.
ABSTRACT Background The widespread use of hyaluronic acid (HA) dermal fillers has been accompanied by an increase in vascular complications, including ischemia and cutaneous necrosis. Although uncommon, filler‐induced vascular compromise represents one of the most severe adverse events in aesthetic medicine and requires immediate recognition and ...
Macarena Olivares, Diego Araya, Eloisa Forero, María José Benoit, Victor Mercado   +4 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

Effects of topical polydeoxyribonucleotide on radiation-induced oral mucositis [PDF]

Technical Innovations & Patient Support in Radiation Oncology, 2018
Oral mucositis, the most common adverse effect of radiotherapy (RT) and/or chemotherapy is observed in almost 97% of patients with head and neck cancer. Although several agents like corticosteroids, lidocaine and vitamins are available for its prevention or management, results are often disappointing.
Podlesko A. M., Ramacciati N., Panzolini S., Saldi S., Fiorucci S., Pierini D., Mancini M., Merolla M. S., Lancellotta V., Aristei C.   +9 more
openaire   +4 more sources

Cutting edge strategies for diabetic wound care: Nanotechnology, bioengineering, and beyond

BMEMat, Volume 4, Issue 1, March 2026.
Graphical abstract illustrates the challenges in diabetic wound healing, covering pathophysiology, formulation hurdles, and emerging therapeutic strategies. It highlights the role of hyperglycemia, formulation complexities, and advanced technologies like bioprinting and AI in improving diabetic wound management. Abstract Diabetic wounds affect millions
Usama Ahmad, Wan Nurhidayah Wan Hanaffi, Anas Islam, Aimen Salman, Mohd Muazzam Khan, Faiyaz Shakeel, Qiang Cai, Xiaojun Cai, Quazi T. H. Shubhra   +8 more
wiley   +1 more source

A Split‐Scar Study: Study of Surgical Scar Using Exosomes

Journal of Cosmetic Dermatology, Volume 25, Issue 3, March 2026.
ABSTRACT Background Exosomes have emerged as a promising therapeutic agent for various dermatological conditions such as acne, atopic dermatitis, and wound healing. This study aims to evaluate exosome's efficacy in improving postoperative scars. Methods Ten patients underwent revision rhinoplasty with autologous costal cartilage, each with a 3 cm ...
Kyung Hwan Jeong, Kui Young Park, Dong‐Woo Jung   +2 more
wiley   +1 more source