Results 11 to 20 of about 9,678 (243)

Antifungal Efficacy of Redox-Active Natamycin against Some Foodborne Fungi—Comparison with Aspergillus fumigatus

open access: yesFoods, 2021
The fungal antioxidant system is one of the targets of the redox-active polyene antifungal drugs, including amphotericin B (AMB), nystatin (NYS), and natamycin (NAT).
Jong H. Kim   +6 more
doaj   +1 more source

Recent Perspectives in the Management of Fungal Keratitis

open access: yesJournal of Fungi, 2021
Mycotic keratitis is common in warm, humid regions with a varying profile of pathogenic fungi according to geographical origin, socioeconomic status, and climatic condition. Clinical diagnosis can be challenging in difficult cases and those refractory to
Nimmy Raj   +5 more
doaj   +1 more source

Repurposing Antifungals for Host-Directed Antiviral Therapy?

open access: yesPharmaceuticals, 2022
Because of their epidemic and pandemic potential, emerging viruses are a major threat to global healthcare systems. While vaccination is in general a straightforward approach to prevent viral infections, immunization can also cause escape mutants that ...
Sebastian Schloer   +2 more
doaj   +1 more source

Postantifungal Effect of Antifungal Drugs against Candida: What Do We Know and How Can We Apply This Knowledge in the Clinical Setting?

open access: yesJournal of Fungi, 2022
The study of the pharmacological properties of an antifungal agent integrates the drug pharmacokinetics, the fungal growth inhibition, the fungicidal effect and the postantifungal activity, laying the basis to guide optimal dosing regimen selection.
Nerea Jauregizar   +5 more
doaj   +1 more source

Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida Species

open access: yesCells, 2023
Candidiasis is a highly pervasive infection posing major health risks, especially for immunocompromised populations. Pathogenic Candida species have evolved intrinsic and acquired resistance to a variety of antifungal medications.
Karolina M. Czajka   +8 more
doaj   +1 more source

Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants

open access: yesJournal of Fungi, 2023
Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also
Joana Branco   +2 more
doaj   +1 more source

Polyene Antibiotics Physical Chemistry and Their Effect on Lipid Membranes; Impacting Biological Processes and Medical Applications

open access: yesMembranes, 2022
This review examined a collection of studies regarding the molecular properties of some polyene antibiotic molecules as well as their properties in solution and in particular environmental conditions.
Tammy Haro-Reyes   +5 more
doaj   +1 more source

New Polyenes from the Marine-Derived Fungus Talaromyces cyanescens with Anti-Neuroinflammatory and Cytotoxic Activities

open access: yesMolecules, 2021
Three new polyene compounds, talacyanols A–C (1–3), along with two known compounds, ramulosin (4) and eurothiocin A (5), were isolated from the marine fungus Talaromyces cyanescens derived from a seaweed Caulerpa sp. Structures of 1–5 were established by
Hee Jae Shin   +7 more
doaj   +1 more source

Polyhydroxyalkanoate/Antifungal Polyene Formulations with Monomeric Hydroxyalkanoic Acids for Improved Antifungal Efficiency

open access: yesAntibiotics, 2021
Novel biodegradable and biocompatible formulations of “old” but “gold” drugs such as nystatin (Nys) and amphotericin B (AmB) were made using a biopolymer as a matrix.
Marina Pekmezovic   +9 more
doaj   +1 more source

Excited singlet states of "hairpin" polyenes [PDF]

open access: yes, 1983
The synthesis and UV-visible, polarized-fluorescence and MCD spectra of 6 U-shaped hairpin polyenes (e.g., I) are reported. Qual. arguments and results of p-electron calcns.
Klingensmith, Kenneth A.   +8 more
core   +1 more source

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