Results 11 to 20 of about 9,678 (243)
The fungal antioxidant system is one of the targets of the redox-active polyene antifungal drugs, including amphotericin B (AMB), nystatin (NYS), and natamycin (NAT).
Jong H. Kim +6 more
doaj +1 more source
Recent Perspectives in the Management of Fungal Keratitis
Mycotic keratitis is common in warm, humid regions with a varying profile of pathogenic fungi according to geographical origin, socioeconomic status, and climatic condition. Clinical diagnosis can be challenging in difficult cases and those refractory to
Nimmy Raj +5 more
doaj +1 more source
Repurposing Antifungals for Host-Directed Antiviral Therapy?
Because of their epidemic and pandemic potential, emerging viruses are a major threat to global healthcare systems. While vaccination is in general a straightforward approach to prevent viral infections, immunization can also cause escape mutants that ...
Sebastian Schloer +2 more
doaj +1 more source
The study of the pharmacological properties of an antifungal agent integrates the drug pharmacokinetics, the fungal growth inhibition, the fungicidal effect and the postantifungal activity, laying the basis to guide optimal dosing regimen selection.
Nerea Jauregizar +5 more
doaj +1 more source
Molecular Mechanisms Associated with Antifungal Resistance in Pathogenic Candida Species
Candidiasis is a highly pervasive infection posing major health risks, especially for immunocompromised populations. Pathogenic Candida species have evolved intrinsic and acquired resistance to a variety of antifungal medications.
Karolina M. Czajka +8 more
doaj +1 more source
Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also
Joana Branco +2 more
doaj +1 more source
This review examined a collection of studies regarding the molecular properties of some polyene antibiotic molecules as well as their properties in solution and in particular environmental conditions.
Tammy Haro-Reyes +5 more
doaj +1 more source
Three new polyene compounds, talacyanols A–C (1–3), along with two known compounds, ramulosin (4) and eurothiocin A (5), were isolated from the marine fungus Talaromyces cyanescens derived from a seaweed Caulerpa sp. Structures of 1–5 were established by
Hee Jae Shin +7 more
doaj +1 more source
Novel biodegradable and biocompatible formulations of “old” but “gold” drugs such as nystatin (Nys) and amphotericin B (AmB) were made using a biopolymer as a matrix.
Marina Pekmezovic +9 more
doaj +1 more source
Excited singlet states of "hairpin" polyenes [PDF]
The synthesis and UV-visible, polarized-fluorescence and MCD spectra of 6 U-shaped hairpin polyenes (e.g., I) are reported. Qual. arguments and results of p-electron calcns.
Klingensmith, Kenneth A. +8 more
core +1 more source

