Results 31 to 40 of about 16,341 (199)

Polyenes in Medium Chain Length Polyhydroxyalkanoate (mcl-PHA) Biopolymer Microspheres with Reduced Toxicity and Improved Therapeutic Effect against Candida Infection in Zebrafish Model

Pharmaceutics, 2022
Immobilizing antifungal polyenes such as nystatin (Nys) and amphotericin B (AmB) into biodegradable formulations is advantageous compared to free drug administration providing sustained release, reduced dosing due to localized targeting and overall ...
Aleksandar Pavic, Zoran Stojanovic, Marina Pekmezovic, Đorđe Veljović, Kevin O’Connor, Ivana Malagurski, Jasmina Nikodinovic-Runic   +6 more
doaj   +1 more source

Antifungal Drugs for Invasive Candida Infections (ICI) in Neonates: Future Perspectives

Frontiers in Pediatrics, 2019
Fungal infections may complicate the neonatal clinical course, and the spectrum of therapies for their treatment in the perinatal period is limited. Polyenes, Azoles and Echinocandins represent the three classes of antifungal drugs commonly used in the ...
Iliana Bersani, Fiammetta Piersigilli, Bianca Maria Goffredo, Alessandra Santisi, Sara Cairoli, Maria Paola Ronchetti, Cinzia Auriti   +6 more
doaj   +1 more source

Luminescent Properties of Arylpolyene Organic Dyes and Cross-Conjugated Ketones Promising for Quantum Optics and Nanophotonics Applications

EPJ Web of Conferences, 2015
The spectral-luminescent properties of some dyes of substituted arylpolyenes and cross-conjugated ketones class in Shpolsky matrices, promising for using in solving quantum optics and nanophotonics, were studied.
Naumova N. L., Vasilyeva I. A.
doaj   +1 more source

Groups of antifungal drugs with role in animal health - Synthesis [PDF]

Medicamentul Veterinar, 2021
Fungal infections are an important part of infectious pathology, their incidence increasing considerably, as a result of the widespread use of antibiotics, corticosteroids, cytostatics and immunosuppressive drugs.
Răzvan F. Moruzi, Eugenia Dumitrescu, Florin Muselin1, Alexandru O. Doma, Corina Vlad, Sergiu Orășan Alic, Romeo Teodor Cristina   +6 more
doaj  

Structural and Electronic Instabilities in Polyacenes: Density Matrix Renormalization Group Study of a Long--Range Interacting Model [PDF]

, 2001
We have carried out Density Matrix Renormalization Group (DMRG) calculations on the ground state of long polyacene oligomers within a Pariser-Parr-Pople (PPP) Hamiltonian.
A. K. Bakshi, Bhargavi Srinivasan, C. A. Coulson, C. Raghu, D. Baeriswyl, D. Yaron, E. Hückel, E. Hückel, E. Jeckelmann, G. Fano, G. Klopman, G. W. Hayden, H. C. Longuet-Higgins, H. Kuhn, H. Labhart, J. A. Pople, J. E. Hirsch, J. E. Lennard-Jones, J. Ooshika, J. Schön, J. Schön, J. Schön, J. Schön, K. Ohno, K. Tanaka, L. Salem, M. Azuma, M. Baldo, M. Baldo, M. Garcia-Bach, M. J. Rice, M. R. Boon, M.-H. Whangbo, M.P. O’Connor, Matthias Vojta, S. Daul, S. Kivelson, S. Mazumdar, S. N. Dixit, S. R. White, S. R. White, S. Ramasesha, S. Ramasesha, S. Ramasesha, S. Ramasesha, T. Yamabe, W. Barford, W. P. Su, W. P. Su, Y. Anusooya Pati, Z. G. Soos, Z. G. Soos, Z. G. Soos   +52 more
core   +2 more sources

Total synthesis of elansolids B1 and B2

Beilstein Journal of Organic Chemistry, 2017
The elansolids A1–A3, B1, and B2 are secondary metabolites formed by the gliding bacterium Chitinophaga sancti. They show antibacterial activity against Gram-positive bacteria.
Liang-Liang Wang, Andreas Kirschning
doaj   +1 more source

Multireference Correlation in Long Molecules with the Quadratic Scaling Density Matrix Renormalization Group [PDF]

, 2006
We have devised and implemented a local ab initio Density Matrix Renormalization Group (DMRG) algorithm to describe multireference nondynamic correlations in large systems.
Garnet Kin-Lic Chan, Johannes Hachmann, Roos B. O., Wim Cardoen   +3 more
core   +2 more sources

TOPOLOGIA DOS ORBITAIS MOLECULARES DE POLIENOS PARA DEDUZIR ENERGIAS RELATIVAS E AVALIAR AROMATICIDADE

Química Nova
A didactic alternative approach is proposed for deducing the molecular orbital topology of acyclic and cyclic polyenes and then evaluating their bonding, antibonding, and nonbonding character.
Silvio Cunha
doaj   +1 more source

Amphotericin B Specifically Induces the Two-Component System LnrJK: Development of a Novel Whole-Cell Biosensor for the Detection of Amphotericin-Like Polyenes

Frontiers in Microbiology, 2020
The rise of drug-resistant fungal pathogens urges for the development of new tools for the discovery of novel antifungal compounds. Polyene antibiotics are potent agents against fungal infections in humans and animals.
Ainhoa Revilla-Guarinos, Franziska Dürr, Philipp F. Popp, Maximilian Döring, Thorsten Mascher   +4 more
doaj   +1 more source

Enzyme-like polyene cyclizations catalyzed by dynamic, self-assembled, supramolecular fluoro alcohol-amine clusters

Nature Communications, 2023
Terpene cyclases enable the synthesis of (poly)cyclic carbon frameworks via ring closure of linear polyenes. Here, the authors report in-situ formed fluorinated-alcohol-amine supramolecular clusters that mimic terpene cyclases for shape-controlled ...
Andreas M. Arnold, Philipp Dullinger, Aniruddha Biswas, Christian Jandl, Dominik Horinek, Tanja Gulder   +5 more
doaj   +1 more source