Results 161 to 170 of about 3,978 (197)
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Liquid chromatographic mass spectrometric methods for the determination of marine polyether toxins.
Bulletin de la Societe de pathologie exotique (1990), 1992Experiments with novel nitrogenous coumarin-based reagents yielded moderately fluorescent derivatives of brevetoxin-3 and ciguatoxin-1. The diethylaminocoumarin-carbamic acid esters of brevetoxin-3 were resolved by high performance liquid chromatography into two derivative peaks that correspond to substitutions at the C-37 and C-41 hydroxyls.
Dickey, R. W. +3 more
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Brevetoxins: unique polyether dinoflagellate toxins
The FASEB Journal, 1989Brevetoxins are lipid‐soluble polyether marine toxins of unique structure and pharmacological function. Toxins are active in vivo in the nanomolar to picomolar concentration range and in vitro in isolated neuromuscular or giant axon preparations and in single‐cell or subcellular model systems.
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Journal of Chromatography A, 2004
The diarrhetic shellfish poisoning (DSP) toxins, okadaic acid (OA), dinophysistoxins (DTX); pectenotoxin-2 (PTX2) and pectenotoxin-2 seco acids, were determined in marine phytoplankton, Dinophysis acuta, and mussels (Mytilus edulis) collected along the southwest coast of Ireland.
Brett R Hamilton +2 more
exaly +7 more sources
The diarrhetic shellfish poisoning (DSP) toxins, okadaic acid (OA), dinophysistoxins (DTX); pectenotoxin-2 (PTX2) and pectenotoxin-2 seco acids, were determined in marine phytoplankton, Dinophysis acuta, and mussels (Mytilus edulis) collected along the southwest coast of Ireland.
Brett R Hamilton +2 more
exaly +7 more sources
Lonspray mass spectrometry of ciguatoxin-1, maitotoxin-2 and -3, and related marine polyether toxins
Natural Toxins, 1994AbstractA range of marine polyether toxins from dinoflagellates were analysed by ionspray mass spectrometry. Ciguatoxin‐1 ([M + H]+ m/z = 1,111.8) purified from several fish species yielded singly charged ions corresponding to the parent ion, sodium and H2O adducts and ions for the loss of up to five H2O molecules.
Richard J. Lewis +2 more
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Toxicon, 2004
Diarretic shellfish poisoning (DSP) is a toxic syndrome associated with the consumption of bivalve molluscs. The DSP toxins are polyether compounds, which include okadaic acid (OA), dinophysistoxins (DTXs), pectenotoxins (PTXs) and pectenotoxin seco acids (PTX2SAs).
Brett R Hamilton, Ambrose Furey
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Diarretic shellfish poisoning (DSP) is a toxic syndrome associated with the consumption of bivalve molluscs. The DSP toxins are polyether compounds, which include okadaic acid (OA), dinophysistoxins (DTXs), pectenotoxins (PTXs) and pectenotoxin seco acids (PTX2SAs).
Brett R Hamilton, Ambrose Furey
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Studies on the biosynthesis of the polyether marine toxin dinophysistoxin-1 (DTX-1)
Tetrahedron Letters, 1994Abstract The biosynthetic origin of DTX-1 is establish on the basis of the NMR spectral data of samples obtained by addition of labelled [1- 13 C 1 ], [2- 13 C 1 ] and [1,2- 13 C 2 ] sodium acetate to artificial cultures of the dinoflagellate Prorocentrum lima.
Manuel Norte +2 more
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Polyether Toxins Implicated in Ciguatera and Seafood Poisoning
1990Naturally occurring polyether compounds are secondary metabolites presumably derived from polyketide biosynthetic pathways. Organisms of Streptomycetales were the first reported biogenetic origin of this class of compounds. Some of the compounds have been used as antibiotics for domestic animals.
Michio Murata, Takeshi Yasumoto
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ChemInform Abstract: Useful Designs in the Synthesis of trans‐Fused Polyether Toxins
ChemInform, 1996AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
E. ALVAREZ +4 more
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Bioscience, Biotechnology, and Biochemistry, 2000
The marine polyether toxin, 45-hydroxyyessotoxin, was isolated together with yessotoxin from the scallop, Patinopecten yessoensis. The 45-hydroxy group in the side chain was esterified with (S)- and (R)-alpha-methoxyalpha-trifluoromethylphenylacetic acids (MTPA).
A, Morohashi +3 more
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The marine polyether toxin, 45-hydroxyyessotoxin, was isolated together with yessotoxin from the scallop, Patinopecten yessoensis. The 45-hydroxy group in the side chain was esterified with (S)- and (R)-alpha-methoxyalpha-trifluoromethylphenylacetic acids (MTPA).
A, Morohashi +3 more
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Synthesis of a marine polyether toxin, okadaic acid (2) — synthesis of segment b
Tetrahedron, 1987Abstract The central synthetic segment B for okadaic acid comprises the carbons from 15 through 27 including 6 asymmetric carbons. Its synthesis started from a D-Glucose derivative, whose carbon was extended twice for the six and five membered etherial ring formation. The original conformation of the sugar was inverted when the spiro-ether was formed
Yoshiyasu Ichikawa +2 more
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