Results 121 to 130 of about 529,599 (321)

In Situ‐Gelling Antimicrobial Poly(oligoethylene glycol methacrylate)‐Based Hydrogels Integrating Bound Quaternary Ammonia Compounds and Antibiotic Functionalities for Effective Infected Wound Healing

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
In situ‐gelling poly(oligoethylene glycol methacrylate) (POEGMA)‐based hydrogels exhibit broad‐spectrum antibacterial activity against both gram‐positive and gram‐negative bacteria based on the dual covalent attachment of quaternary ammonium (QA) groups and the antibiotic ciprofloxacin (CIP) into the hydrogel networks, enabling effective in vivo burn ...
Fei Xu   +8 more
wiley   +1 more source

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan   +13 more
wiley   +1 more source

Self‐Doped and Biodegradable Glycosaminoglycan‐PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC‐Derived Cardiomyocytes

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 9, April 4, 2025.
The electrical properties and performance of conductive hydrogels based on sulfated‐glycosaminoglycan‐PEDOT (poly 3,4‐ethylenedioxythiophene) brush copolymers is studied, showing that the higher sulfation degree of heparin confers hydrogels with the highest conductivity.
Daniel Hachim   +11 more
wiley   +1 more source

Mechanically and Chemically Defined PEG Hydrogels Improve Reproducibility in Human Cardioid Development

open access: yesAdvanced Healthcare Materials, EarlyView.
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song   +6 more
wiley   +1 more source

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