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The Toxicology of the Polyethylene Glycols*
Journal of the American Pharmaceutical Association (Scientific ed.), 1950Information developed during recent years upon the toxicological actions of the fluid and solid polyethylene glycols is summarized. This information has been re-interpreted and supplemented. Evidence presented in this report confirms the earlier work indicating that acute oral toxicity, dermal toxicity, and irritating properties of the polyethylene ...
H F, SMYTH, C P, CARPENTER, C S, WEIL
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The Biodegradation of Polyethylene Glycols
1978Publisher Summary This chapter discusses the biodegradation of polyethylene glycols. The glycols are compounds composed of from one to four units of ethylene oxide attached by ether linkages, and terminated with hydroxyl groups. The polyethylene glycols (PEGS) are ethylene oxide polymers which are represented by the following general formula: OCH ...
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Hypersensitivity to Polyethylene Glycols
The Journal of Clinical Pharmacology, 2013Sapna, Shah +3 more
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Applied Biochemistry and Biotechnology, 1995
The increasing demand of synthetic oligonucleotides for therapeutic and diagnostic purposes can be hardly satisfied by simply up-scaling the commercial synthesizers. The introduction of a liquid-phase method that utilizes a polymeric support soluble into the reaction media can overcome the shortcomings related to the heterogeneity of the solid phase ...
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The increasing demand of synthetic oligonucleotides for therapeutic and diagnostic purposes can be hardly satisfied by simply up-scaling the commercial synthesizers. The introduction of a liquid-phase method that utilizes a polymeric support soluble into the reaction media can overcome the shortcomings related to the heterogeneity of the solid phase ...
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