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Polyethylene glycol-induced pancreatitis
Gastrointestinal Endoscopy, 2000Polyethylene glycol-electrolyte solutions are commonly used for bowel preparation for a variety of endoscopic, radiologic, and surgical procedures. Adverse side effects such as nausea, abdominal bloating, and vomiting are common; however, severe complications are uncommon.
James A. Harris, Dion L. Franga
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Polyethylene Glycol as a Binder for Tablets
Journal of Pharmaceutical Sciences, 1977Polyethylene glycol 6000 was evaluated as a binder for the direct compression of 11 tablet formulations. Six formulations compressed quite well, and the resulting tablets were satisfactory in all respects. To evaluate stability, actual shelflife studies were considered more appropriate than the accelerated studies. After a shelflife of 3 years, five of
P.V. Sheth, R.C. Shah, P.V. Raman
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The Biodegradation of Polyethylene Glycols
1978Publisher Summary This chapter discusses the biodegradation of polyethylene glycols. The glycols are compounds composed of from one to four units of ethylene oxide attached by ether linkages, and terminated with hydroxyl groups. The polyethylene glycols (PEGS) are ethylene oxide polymers which are represented by the following general formula: OCH ...
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Radioprotective Effect of Polyethylene Glycol
Radiation Research, 1986Polyethylene glycol of molecular weight 400 (PEG-400) had a radioprotective effect of about 20% against lethality when given ip 20 min prior to single or fractionated X-ray doses to the head and neck. Dose modification factors (DMF) based on LD50/15 values ranged from 1.14 to 1.24. A similar DMF of 1.12 based on LD50/30 values was obtained using single
Cathy H. Seymore +4 more
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Osmotic effects of polyethylene glycol
Gastroenterology, 1988Polyethylene glycol (PEG) has been used to increase the osmotic pressure of fluids used to cleanse the gastrointestinal tract. However, little is known about its osmotic activity. To investigate this activity systematically, solutions of PEG of differing molecular weights were made and subjected to measurement of osmolality by both freezing point ...
Michael Emmett +3 more
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Toxicity of topical polyethylene glycol
Toxicology and Applied Pharmacology, 1982Abstract An animal model was developed to study the potential toxicity resulting from repeated, topical applications of a polyethylene glycol-based antimicrobial cream. Applications of this cream to open wounds in rabbits produced the same syndrome observed in the burn patients treated with this agent.
Richard F. Edlich +5 more
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Precipitation of collagens by polyethylene glycols
Analytical Biochemistry, 1984Types I, II, and III collagens are readily precipitated at neutral pH by polyethylene glycols (PEG). As the molecular weight fraction of the polyethylene glycols increases, they become more effective as precipitants on a weight basis. The amount of PEG required for precipitation depends on the pH, the ionic strength, and the nature of the buffer or ...
John F. Bateman +2 more
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Use of Polyethylene Glycol in Biology
Nature, 1961IN a recent paper, I. Mackenzie Lamb1 directed attention to the use of polyethylene glycol (‘Carbowax’) for the permanent preservation of algal material for microscopic study. He shows that it is practicable to preserve algae in the dry state embedded in polyethylene glycol and mounted on cards. When a portion is required for study, part of the card is
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The Immunogenicity of Polyethylene Glycol: Facts and Fiction
Pharmaceutical Research, 2013An increasing number of pegylated therapeutic proteins and drug targeting compounds are being introduced in the clinic. Pegylation is intended to increase circulation time and to reduce an immunogenic response. Recently however a number of publications have appeared claiming that the polyethylene glycol (PEG) moiety of these products in itself may be ...
Huub Schellekens +2 more
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SENSITIZATION TO POLYETHYLENE GLYCOLS (CARBOWAXES®)
Archives of Dermatology, 1950THE POLYETHYLENE glycols are condensation or polymerization products of ethylene glycol of relatively high molecular weights. The heavier and more solid of these have been called carbowaxes.® The polyethylene glycols commonly used range from polyethylene glycol 400, a thick liquid of a consistency similar to glycerin, through carbowax® 1500, an ...
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