Results 181 to 190 of about 815,697 (298)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

open access: yesPhytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li   +14 more
wiley   +1 more source

Macrohormones in endocrinology: prevalence, clinical impact, and diagnostic approaches. [PDF]

open access: yesFront Endocrinol (Lausanne)
Bronisławska A   +6 more
europepmc   +1 more source

Plant‐Derived Extracellular Vesicles: Biogenesis, Function, and Application in Cancer Immunotherapy

open access: yesPhytotherapy Research, EarlyView.
This illustration shows the biogenesis pathways of edible and medicinal plant‐derived extracellular vesicles (PDEVs) and their therapeutic effects following uptake in the human body, highlighting their potential for application in cancer immunotherapy. ABSTRACT Plant‐derived extracellular vesicles (PDEVs) are nanoscale, lipid bilayer‐enclosed vesicles ...
Guosheng Li   +4 more
wiley   +1 more source

Role of 1D and 2D Materials in Achieving Transparent and Flexible Lithium‐Ion Batteries for Wearable Electronics

open access: yesSmall, EarlyView.
Hybrid 1D–2D architectures redefine material design strategies for TFLIBs by decoupling competing performance parameters. This approach accelerates the transition of TFLIBs from proof of concept to practical wearable technologies. ABSTRACT Transparent and flexible lithium‐ion batteries (TFLIBs), enabled by advanced nanomaterials and flexible ...
Raviraj Madesan, Anand Sreekantan Thampy
wiley   +1 more source

Asymptotic r2 Enhancement in Formulation‐Optimized Lipid‐Iron Oxide Nanoparticles for Assessing Glioblastoma Heterogeneity at Ultrahigh‐Field MRI

open access: yesSmall, EarlyView.
Lipid‐coated superparamagnetic iron oxide nanoparticles (LSPIONs) are developed as MRI‐visible lipid nanocarriers for glioblastoma imaging. By tuning nanoparticle size and SPION loading, their transverse relaxivity (r2) can be systematically controlled over one order of magnitude, reaching 390 mm−1 s−1 at 9.4 T.
Marcos Bazarra‐Barreiros   +8 more
wiley   +1 more source

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