Results 201 to 210 of about 4,131 (247)
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Stereoselective access to polyfunctionalized decalins

Tetrahedron Letters, 1994
As a model of a stereoselective approach to ajugareptansin 1, a versatile and straightforward access to polyfunctionalized cis or trans decalins is presented. It is based on a Lewis acid-mediated addition of furan to the unsaturated ketoester 3 followed by oxidative opening of the furan to give cis decalins by an aldolisation process.
Poirel, Cyrille   +2 more
openaire   +2 more sources

Synthesis of polyfunctionally substituted pyridazines

Liebigs Annalen der Chemie, 1990
AbstractThe pyridazines 3, 4, 5, and 7 were obtained by reaction of the hydrazone derivatives 2 with several reagents. By treatment of 5 with acetic acid/hydrochloric acid, the pyrazolo[4,3‐c]‐pyridazine 6 was formed. The pyrido‐pyridazine derivatives 8 and 9 were obtained by reaction of 2 and 3 with malononitrile and ethyl cyanoacetate, respectively ...
Said Ahmed Soliman Ghozlan   +3 more
openaire   +1 more source

Construction of Polyfunctionalized 6-5-5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction.

Organic Letters, 2020
A novel one-pot semipinacol rearrangement/Michael addition/Henry reaction of vinylogous α-ketols with nitroolefins has been achieved through the promotion of two Lewis acids, namely, TMSOTf and TiCl4, at temperatures between 0 and -78 °C.
Fu-Ping Zhu   +5 more
semanticscholar   +1 more source

Stereospecific Synthesis of Trifluoromethyl‐Substituted Polyfunctionalized Cyclopropanes.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Yi Wang   +3 more
openaire   +1 more source

ChemInform Abstract: Studies with Polyfunctionally Substituted Heteroaromatics: A New Route to Polyfunctionally Substituted Anellated Mercaptophthalazines.

ChemInform, 1994
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
M. H. ELNAGDI   +3 more
openaire   +1 more source

One-Pot Synthesis of Polyfunctionalized Cyclic Urea Derivatives

Organic Letters, 2003
[reaction: see text] Unexpectedly, imidazolidin-2-ones are easily obtained from beta-keto esters upon treatment with tert-butyl nosyloxycarbamate and calcium oxide under mild conditions. The structure of the product was established by X-ray crystallography.
FIORAVANTI, Stefania   +4 more
openaire   +4 more sources

A cytofluorimetric assay to evaluate T cell polyfunctionality

2020
The magnitude and the quality of T-cell response are critical endpoints in the immune-monitoring of cancer patients. The release of cytokines and lytic factors by T cells operate in each phase of the cancer immunity cycle. The simultaneous cytokine production, defined as T-cell polyfunctionality, is a dynamic state of different T-cell subsets and may ...
Belinda, Palermo   +3 more
openaire   +2 more sources

ChemInform Abstract: Studies with Polyfunctionally Substituted Heteroaromatics: Synthesis of Some New Polyfunctionally Substituted Pyridazine Derivatives.

ChemInform, 1994
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
S. E. ZAYED   +3 more
openaire   +1 more source

Efficient Synthesis of Polyfunctionalized Pyrimidine Derivatives

Synlett, 2016
A simple and direct procedure was developed for the synthesis of a novel series of polyfunctionalized pyrimidines. They were prepared via reaction of N-(substituted carbamothioyl)benzimidamides (prepared from the reaction of benzimidamide hydrochloride and isothiocyanates) and malononitrile in the presence of CuBr/Et3N in DMF at 80 °C.
Abbas Shafiee   +4 more
openaire   +1 more source

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